ILC TNMU | Team

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Education and academic degrees

2010: Doctor of Medical Sciences, O. O. Bohomolets Institute of Physiology, National Academy of Sciences of Ukraine.
2004: Candidate of Medical Sciences, O. O. Bohomolets Institute of Physiology, National Academy of Sciences of Ukraine.
1996: Master of Medicine (Pediatrics), Zaporizhzhia State Medical University.

Positions

2020 – present: Professor, Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University.
2015–2020: Professor and Head of the Department of Microbiology, Virology and Immunology, Zaporizhzhia State Medical University.
2010–2015: Associate Professor and Head of the Department of Microbiology, Virology and Immunology, Zaporizhzhia State Medical University.

Project management (grants)

2026–2028: Principal Investigator of the National Research Foundation of Ukraine grant “Improving the effectiveness of limb function restoration in military personnel with amputations and traumatic injuries”.
2023–2025: Principal Investigator of the RECOOP Research & Development Program project “Comprehensive analysis of genetic predictors of MAFLD development in patients with COVID-19” (Grant #36-CSMC Senior Scientists).
2023–2024: Principal Investigator of the STCU program “Virtual Scientist Engagement Fellowship Program for Vulnerable Ukrainian Scientists” (Grant Agreement #2025-VSE).
2020–2021: Co-leader of the National Research Foundation of Ukraine grant “Structural and immune disorders in target organs induced by SARS-CoV-2: the search for predictors of disease severity and prediction of the risk of complications”.

Supervision of students and PhD candidates

Zaporizhzhia State Medical and Pharmaceutical University: 10 master’s students, 8 PhD candidates.
I. Horbachevsky Ternopil National Medical University: 2 master’s students, 2 PhD candidates.
Danylo Halytsky Lviv National Medical University: 1 PhD candidate.
Kharkiv National Medical University: 1 PhD candidate.

Other professional experience and memberships

Editorial work: Guest Editor of the international journals Frontiers in Molecular Biosciences (2024), Viruses (2024, 2025) and Frontiers in Bioengineering and Biotechnology (2025).
Peer review: reviewer of more than 20 manuscripts for Frontiers in Microbiology, Frontiers in Immunology and Frontiers in Endocrinology.
Society memberships: American Society for Microbiology (ASM) (since 2022), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) (since 2022), S. M. Vynohradskyi Society of Microbiologists of Ukraine (since 2017).
WHO certification: mhGAP training program (2024–2025) “Management of common mental disorders in primary health care”.

Research output and key publications

Over the course of his career he has published more than 150 works. In the last five years, more than 80 papers have appeared in leading first-quartile (Q1) international journals.

Halabitska I, Petakh P, Buchynskyi M, Kamyshna I, Lushchak O, Kamyshnyi O. War, diet, and PTSD in Ukrainian youth. Scientific Reports. 2026;16(1). doi:10.1038/s41598-025-31138-3
Haeuser E, Byrne S, Nguyen J, Raggi C, McLaughlin SA, Bisignano C, et al. Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023. The Lancet. 2025;406(10500):235-60. doi:10.1016/S0140-6736(25)01037-2
Ravlo E, Ianevski A, Schjølberg JO, Solvang V, Dumaru R, Lysvand H, et al. Synergistic combination of orally available safe-in-man pleconaril, AG7404, and mindeudesivir inhibits enterovirus infections in human cell and organoid cultures. Cellular and Molecular Life Sciences. 2025;82(1). doi:10.1007/s00018-025-05581-4
Halabitska I, Petakh P, Kamyshnyi O. Metformin as a disease-modifying therapy in osteoarthritis: bridging metabolism and joint health. Front Pharmacol. 2025;16:1567544. doi:10.3389/fphar.2025.1567544
Duve K, Shkrobot S, Petakh P, Oksenych V, Kamyshnyi O. Clinical, Neuroimaging, and Genetic Markers Associated with Cognitive and Functional Outcomes After Traumatic Brain Injury. J Clin Med. 2025;14(8):2796. doi:10.3390/jcm14082796
Halabitska I, Petakh P, Kamyshna I, Oksenych V, Kainov DE, Kamyshnyi O. The interplay of gut microbiota, obesity, and depression: insights and interventions. Cell Mol Life Sci. 2024;81(1):443. doi:10.1007/s00018-024-05476-w
Halabitska I, Petakh P, Oksenych V, Kamyshnyi O. Predictive analysis of osteoarthritis and chronic pancreatitis comorbidity. Front Endocrinol. 2024;15:1492741. doi:10.3389/fendo.2024.1492741
Petakh P, Oksenych V, Kamyshna I, Boisak I, Lyubomirskaya K, Kamyshnyi O. PTSD, gut microbiota, and inflammatory biomarkers: a meta-analysis. Front Immunol. 2024;15:1349883. doi:10.3389/fimmu.2024.1349883
Petakh P, Oksenych V, Kamyshnyi A. The F/B ratio as a biomarker for inflammation in COVID-19 and T2D: Impact of metformin. Biomed Pharmacother. 2023;163:114892. doi:10.1016/j.biopha.2023.114892
Kamyshnyi A, Koval H, Kobevko O, Buchynskyi M, Oksenych V, Kainov D, et al. Therapeutic Effectiveness of Interferon-a2b against COVID-19 with Community-Acquired Pneumonia: The Ukrainian Experience. Int J Mol Sci. 2023;24(8). doi:10.3390/ijms24086887

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Education

2026: Award of professional qualification in Analytical and Control Pharmacy, National University of Pharmacy.
2021: Academic title of Professor, TNMU.
2019: Doctor of Pharmaceutical Sciences, specialty 15.00.02 Pharmaceutical Chemistry and Pharmacognosy, Danylo Halytsky Lviv National Medical University.
2016: Academic title of Associate Professor, Ternopil State Medical University.
2013: Candidate of Pharmaceutical Sciences, specialty 15.003 Standardization and Organization of Medicines Production, National University of Pharmacy.
2009–2010: Master’s degree (with distinction) and internship at I. Horbachevsky Ternopil State Medical University, specialty “Pharmacy”.
2004–2009: I. Horbachevsky Ternopil State Medical University, specialty “Pharmacy” (diploma with distinction).

Positions

2026 – present: Head of the Drug Quality Control Research Laboratory, I. Horbachevsky TNMU.
2019 – present: Head of the Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2015–2019: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2014–2015: Senior Lecturer, Department of Pharmaceutical Chemistry, I. Horbachevsky TSMU.
2013–2017: Deputy Dean of the Faculty of Pharmacy, I. Horbachevsky TSMU.
2010–2014: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TSMU.

Project management experience

2024–2026: Scientific supervisor of the research project “Development and validation of analytical and bioanalytical methods for the determination of medicinal products; identification of original functional theophylline derivatives with antiradical properties” (0124U000057).
2024: Scientific supervisor of the state-funded research project “Development of environmentally safe analytical methods for the determination of APIs from the calcium ion antagonist group in medicinal products” (0124U000065).
2023–2026: Scientific supervisor of “Wearable Smart Patches for Multimodal Wound Healing — DRESWOUTRE” (NATO SPS Project G6031).
2020–2023: Scientific supervisor of the state-funded research project “Development of original combinations of antihypertensive agents, their analysis and standardization” (state registration No. 0120U104201).

Other relevant professional experience

2026 – present: Expert of the European Pharmacopoeia, Group 10B.
2026 – present: Founder and Director of the NGO “Scientific Society for Pharmaceutical Analytics”.
2025 – present: Member of the NGO “Ukrainian Society for Medicinal Chemistry”.
2023–2026: Expert of the Ministry of Health of Ukraine in “Pharmacy. Clinical Pharmacy. Clinical Pharmacology”.
2020 – present: Member of the editorial boards of Universal Journal of Pharmaceutical Research, International Journal of Green Pharmacy, B R Nahata Smriti Sansthan International Journal of Pharmaceutical and Biological Archive, ScienceRise: Pharmaceutical Science, Scientific Reports and others.

Key research and professional skills

Pharmaceutical analysis: development and validation of modern chromatographic and spectrophotometric methods for analyzing medicinal products, impurity control, and identification and quantification of active pharmaceutical ingredients.
Bioanalytical methodology: development and optimization of analytical approaches for determining drugs and metabolites in biological matrices; HPLC/UPLC, LC-MS/MS, sample preparation techniques and validation.
Standardization of medicinal products: pharmacopoeial analysis, development of specifications, quality control and validation of analytical methods in accordance with Ph. Eur., USP, ICH, EMA and FDA requirements.
Green, white and blue chemistry, ecology: development of environmentally safe analytical methods (AGREE, GAPI/MOGAPI, AGSA, CaFRI, CACI) and minimization of toxic solvents and waste.
Quality by Design (QbD): application of Design of Experiments (DoE), risk assessment, identification of critical method parameters and optimization of chromatographic conditions.
Chromatographic technologies: HPLC/UPLC-PDA/DAD, LC-MS/MS; development of isocratic and gradient methods, analysis of impurities, degradation products and drug stability.
Analytical chemistry and quality control: studies of stability, impurity profile, purity and authenticity of medicinal products; application of modern approaches to pharmaceutical quality control.
Academic and teaching competences: teaching pharmaceutical chemistry; participation in international grant projects; preparation of papers for international peer-reviewed journals.

Key publications

Development of a Novel, Fast, Simple HPLC method for determination of atorvastatin and its impurities in tablets // Scientia Pharmaceutica. 2021. Vol. 89. P. 1-16.
New liquid chromatography assays for simultaneous quantification of antihypertensives atenolol and valsartan in their dosage forms // Journal of Separation Science. 2021. Vol. 44. P. 565-575.
Development of a novel, fast, simple, nonderivative HPLCmethod with direct UV measurment for quantification of memantine hydrochloride in tablets // Journal of Separation Science. - 2020. Vol. 43. P. 3482-3490.
A validated LC-MS/MS method for the quantification of amlodipine, bisoprolol, enalapril and enalaprilat Application to pharmacokinetic study in healthy volunteers // Microchemical Journal. 2020. Vol. 155. P. 104700.
Typlynska K., Kondratova Y., Logoyda L. Development of methods of quality control of the tablets «Ramipril» // Sci. Pharm. 2023. Vol. 91.21.
Piponski M., Stoimenova T. B., Melnyk T. et al. Concepts for new rapid simple HPLC method for quantification of fosfomycin trometamol in pharmaceutical dosage forms with direct UV detection // Sci. Pharm. 2022. Vol. 90. - P. 35.
Asmari M., Wang X., Casado N. et al. Chiral Monolithic Silica-Based HPLC Columns for Enantiomeric Separation and Determination: Functionalization of Chiral Selector and Recognition of Selector-Selectand Interaction // Molecules. 2021. Vol. 26. - P. 5241.
Shulyak N., Piponski M., Kovalenko S. et al. Chaotropic salts impact in HPLC approaches for simultaneous analysis of hydrophilic and lipophilic drugs // Journal of Separation Science. 2021. Vol. 44. P. 2908-2916.
Horyn M., Kryskiw L., Kucher T. et al. Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: application to tablet analysis // BMC Chemistry. 2025. Vol. 19, 8.
Halka L., Kucher T., Piponski M. et al. Four ecofriendly spectrophotometric methods for the determination of perindopril through derivatization with sulphophtalein dyes: application to tablet analysis // BMC Chemistry. 2024. - Vol. 18.
Piponski M., Halka L., Kucher T. et al. Concepts for a new rapid and simple hplc method for simultaneous determination of rosuvastatin and perindopril in dosage forms. // Sep Sci plus. -2024. -e202400101.
Piponski M., Topkoska-Naumoska M., Slaveska-Spirevska I. et al. Concepts and principles for new rapid simple liquid chromatography method for quantification of antioxidants resveratrol, vitamin E, and coenzyme Q10 in capsules with high-performance liquid chromatography with a photo-diode array detector // J Sep Sci. -2024. Vol 47. P. 2300585.
Al-Karmalawy A. A., El-Subbagh H. I., Logoyda L. et al. Editorial: Recent advances in the research and development of kinase-inhibitory anticancer molecules // Front. Chem. 2023. Vol. 11. P. 1328424.
Abdel-Megied A. M., Kovalenko S., Elbarbry F. A. et al. LC-MS/MS bioanalytical method for the quantitative analysis of nifedipine, bisoprolol, and captopril in human plasma: Application to pharmacokinetic studies // Biomedical Chromatography. - 2023. e5664.
Hussein G. O., Rezk R. M., Logoyda L., Wadie M. Eco-friendly spectrophotometric methods for resolving the spectral inference of benzalkonium chloride during alcaftadine and ketorolac tromethamine quantification // Analytical Science Advances. 2025. Vol. 6:e70028.
Havrylenko O., Kondratova Y., Ivanets L., Berdey I., Logoyda L. Optimization of HPLC methods for the development of quality control methods of combined powder formulations with paracetamol, phenylephrine hydrochloride, pheniramine maleate // BMC Chemistry. 2025. Vol. 19, 145.
Piponski M., Beneta A., Stefkov G. et al. Approaches to the Development of New Simple Rapid HPLC-Photodiode Array Method for the Simultaneous Determination of Levomenthol and Ibuprofen in Gel Pharmaceutical Formulation // Sep Sci plus. - 2025. - Vol. 8: e70061.
Piponski M., Druchok M., Horyn M. et al. Impact of chaotropic salts on separation simplification on liquid chromatographic determination of cisplatin, pheniramine and their related compound // BMC Chemistry. - 2026. – Vol.20: 59.
Wadie M., Badr K. A., Hosny A. A. et al. A Novel ultra-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry method for quantification of imeglimin in human plasma: application to a bioequivalence study // Analytical Science Advances. - 2026. - Vol. 7; 1: e70079.
Havrylenko O., Kondratova Y., Typlynska K., Logoyda L. Development and validation of HPLC methods for the quantitative determination and related impurities of naftifine hydrochloride in solution and cream dosage forms // Sci. Pharm. - 2026. - 94, 5.

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Education

2026: Award of professional qualification in Analytical and Control Pharmacy, National University of Pharmacy.
2023: PhD, specialty 226 Pharmacy, Industrial Pharmacy, TNMU.
2020–2021: Internship at I. Horbachevsky TNMU, specialty Pharmacy.
2015–2020: I. Horbachevsky TNMU, specialty 226 “Pharmacy, Industrial Pharmacy” (diploma with distinction).

Positions

2025 – present: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2021–2025: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2019–2021: Laboratory Technician, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.

Project work and professional experience

2026: Co-founder of the NGO “Scientific Society for Pharmaceutical Analytics”.
2025: Member of the Ukrainian Society for Medicinal Chemistry.
2024–2026: Co-investigator of the TNMU research project “Development and validation of analytical and bioanalytical methods for the determination of medicinal products; identification of original functional theophylline derivatives with antiradical properties” (01240000057).
2024: Responsible investigator of the TNMU state-funded research project “Development of environmentally safe analytical methods for the determination of APIs from the calcium ion antagonist group in medicinal products” (01240000065).
2020–2022: Co-investigator of the TNMU research project “Targeted search for biologically active substances among 7,8-disubstituted theophyllines…” (01210100062).
2020–2022: Technician on the TNMU state-funded research project “Development of original combinations of antihypertensive agents, their analysis and standardization” (01200104201).

Key research and professional skills

Chromatographic analysis (HPLC): practical experience in developing, optimizing and validating high-performance liquid chromatography methods, using the Analytical Quality by Design (AQbD) concept and DoE.
Spectrophotometric analysis: practical experience in developing and validating UV-visible spectrophotometric methods and building calibration models.
Pharmaceutical analysis and quality control: experience in physicochemical testing, identification and quantification in accordance with the requirements of the State Pharmacopoeia of Ukraine, Ph. Eur. and ICH.
Statistical processing: use of Minitab, GraphPad Prism, Microsoft Excel and IBM SPSS to evaluate validation parameters and measurement uncertainty.
Green pharmaceutical analysis: assessment of the environmental profile of analytical methods using metrics (AGREE, ComplexGAPI, MOGAPI).
Academic and teaching competences: teaching the subject “Pharmaceutical Chemistry”, supervising student research and preparing publications.

Key publications

Практичні аспекти розробки ВЕРХ методик для фармацевтичного аналізу: монографія / Логойда Л. С., Горин М. М., Піпонскі М. та ін. - Тернопіль: ТНМУ, 2026. - 852 c. ISBN 978-966-673-541-9.
Piponski M., Druchok M., Horyn M. et al. Impact of chaotropic salts on separation simplification on liquid chromatographic determination of cisplatin, pheniramine and their related compound // BMC Chemistry. - 2026. - Vol.20: 59.
Horyn M., Piponski M., Kryskiw L. et al. QbD-driven RP-HPLC method for the simultaneous analysis of dihydropyridines calcium channel blockers in pharmaceuticals // BMC Chemistry - 2025. Vol 19(1).
Piponski M., Beneta A., Stefkov G. et al. Approaches to the Development of New Simple Rapid HPLC-Photodiode Array Method for the Simultaneous Determination of Levomenthol and Ibuprofen... // Sep Sci plus. 2025. - Vol. 8: e70061.
Horyn M., Kryskiw L., Kucher T. et al. Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye... // BMC Chemistry. 2025. Vol. 19, 8.
Halka L., Kucher T., Piponski M. et al. Four ecofriendly spectrophotometric methods for the determination of perindopril through derivatization with sulphophtalein dyes... // BMC Chemistry. 2024. Vol. 18.
Piponski M., Halka L., Kucher T. et al. Concepts for a new rapid and simple hplc method for simultaneous determination of rosuvastatin and perindopril in dosage forms. // Sep Sci plus. 2024. e202400101.
Piponski M., Horyn M., Grncaroska K. et al. Concepts for a new rapid and simple HPLC method for simultaneous determination of Metoprolol and Meldonium in pharmaceutical dosage forms // Sci. Pharm. 2022. Vol. 90. P. 65.
Druchok M., Piponski M., Horyn M. et al. The usage of salts of chaotropic anions for the development of HPLC method for the simultaneous determination of cisplatin and carboplatin... // ScienceRise: Pharmaceutical Science. 2025. Vol. 5 (57). P. 29-36.

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Education and academic degrees

2026: Award of professional qualification in Analytical and Control Pharmacy, National University of Pharmacy.
2017: Academic title of Associate Professor, Ternopil State Medical University.
2014: Candidate of Pharmaceutical Sciences, specialty 15.00.01 — Drug Technology, Organization of Pharmacy and Forensic Pharmacy, Zaporizhzhia State Medical University.
2008: Master of Pharmacy, I. Horbachevsky TSMU.
2006: Master of Finance, Ternopil State University of Economics.

Positions

Since 2018: Deputy Dean of the Faculty of Pharmacy, I. Horbachevsky TNMU.
Since 2016: Associate Professor, I. Horbachevsky TNMU.
2009–2016: Assistant of the Department, I. Horbachevsky TSMU.
2007–2009: Pharmacist, “Remedi R” LLC.

Project management (grants and research projects)

Since 2026: Investigator on a research project concerning methodological approaches to comprehensive marketing, pharmacoeconomic and technological studies in drug development.
2023–2026: Investigator on the research project “Design of studies in pharmaceutical drug development, marketing and pharmacoeconomic analysis, and pharmacological clinical activity”.
2020–2023: Investigator on a research project on the creation of targeted-action medicinal products.
2015–2020: Investigator on a research project on marketing, pharmacoeconomic and technological studies.

Professional experience and key skills

Pharmaco-technological testing: comprehensive pharmaco-technological studies of medicinal products and determination of optimal process parameters.
Research interests: the dissolution test, disintegration of tablets and capsules, tablet friability, sieve analysis and tablet crushing strength.
Memberships: member of the NGO “Association of Homeopaths of Ukraine” (since 2025) and the NGO “All-Ukrainian Pharmaceutical Chamber” (since 2021).

Key publications

Optimization of HPLC methods for the development of quality control methods of combined powder formulations with paracetamol, phenylephrine hydrochloride, pheniramine maleate / O. Havrylenko et al. BMC Chemistry. 2025. Vol. 19, no. 1.
Дослідження вітчизняного ринку гомеопатичних лікарських засобів, що діють на нервову систему / Г. Р. Козир та ін. Фармацевтичний часопис. 2025. № 2. С. 68-76.
Біофармацевтичні та мікробіологічні обґрунтування складу гелю для фіксації зубних протезів / Г. Р. Козир та ін. Здобутки клінічної і експериментальної медицини. 2025. № 2. C. 84-91.
Технологічні та біофармацевтичні дослідження щодо створення косметичного засобу на основі фітосубстанції Кермека Гмеліна / О. М. Барна та ін. Фармацевтичний часопис. 2025. № 1. С. 15-23.
Slobodianiuk L., Budniak L., Marchyshyn S., Berdey I., Slobodianiuk O. Study of the hypoglycemic effect of the extract from the tubers of Stachys sieboldii MIQ. // Pharmacologyonline. 2021. Vol. 2. P. 167-178.
Вплив допоміжних речовин на вивільнення біологічно активних сполук із суміші екстракту сухого перетинок грецького горіха / М.М. Васенда, Ю.Ю. Пласконіс, Г.Р. Козир, І.І. Бердей // Фітотерапія. Часопис. 2018. № 4. С. 61-63.
Чорний Р.С., Чорна Н.П., Бердей І.І. Активізація інвестиційної діяльності України в умовах економіко-політичної нестабільності // Соціально-економічні проблеми сучасного періоду України. 2018. Вип. 3 (131). С. 114-120.
Романіна Д.М., Бердей І.І., Гладишев В.В., Лисянська Г.П. Вивчення впливу концентрації поверхнево-активних речовин на вивільнення празіквантелу з ректальних супозиторіїв // Фармацевтичний журнал. 2016. №6. С. 66-71.

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Education and academic degrees

2026: Award of professional qualification in Analytical and Control Pharmacy, National University of Pharmacy.
2016: Academic title of Associate Professor, Ternopil State Medical University.
2014: Candidate of Pharmaceutical Sciences, specialty 15.00.03 — Standardization and Organization of Medicines Production, National University of Pharmacy.
2005–2006: Internship in “General Pharmacy”, Ivano-Frankivsk State Medical University.
2000–2005: I. Horbachevsky TSMU, specialty “Pharmacy” (diploma with distinction).

Positions

Since 2014: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2008–2014: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TSMU.
2006–2008: Pharmacist at the “Era-Ter” pharmacy, Ternopil.

Experience in projects and research

2024–2026: Co-investigator of the research project “Development and validation of analytical and bioanalytical methods for the determination of medicinal products; identification of original functional theophylline derivatives…” (01240000057).
2024: Co-investigator of the state-funded research project “Development of environmentally safe analytical methods for the determination of APIs from the calcium ion antagonist group in medicinal products” (01240000065).
2020–2022: Co-investigator of the state-funded research project “Development of original combinations of antihypertensive agents, their analysis and standardization” (01200104201).
Memberships: co-founder of the NGO “Scientific Society for Pharmaceutical Analytics” (2026); member of the Ukrainian Society for Medicinal Chemistry (since 2025).

Key research and professional skills

Standardization of medicinal products: experience in developing and harmonizing specifications for plant raw materials and multi-component products in accordance with the State Pharmacopoeia of Ukraine, Ph. Eur. and ICH.
Pharmaceutical analysis: physicochemical analysis of APIs and finished medicinal products (identification, quantification, purity).
Chromatographic and spectral analysis: practical experience in TLC analysis and in the development and validation of UV-visible spectrophotometric methods for quantification.
Environmentally safe pharmaceutical analysis: assessment of the greenness of methods using AGREE, ComplexGAPI and MOGAPI, and implementation of green, blue and white chemistry principles.
Statistical processing: mathematical data processing and construction of calibration models (Minitab, GraphPad Prism, SPSS).

Key publications

Method of obtaining and standartizing extracts of creeping thyme: monograph / Holovnia S. B. et al. Karlsruhe, Germany, Book 13.(2), 2022. 147 p. ISBN 978-3-949059-62-9.
Andrii Zhuravel, Marjan Piponski, ... Nadiya Zarivna, et al. Simultaneous ecofriendly HPLC determination of clotrimazole, miconazole, metronidazole, and lidocaine in pharmaceutical dosage forms // BMC Chemistry. 2026. (Q2).
Piponski M., Druchok M., Horyn M., Zarivna N. et al. Impact of chaotropic salts on separation simplification on liquid chromatographic determination of cisplatin, pheniramine and their related compound // BMC Chemistry. 2026. Vol.20: 59. (Q2).
Horyn M., Piponski M., Kryskiw L., Rezk M. R., Zarivna N. et al. QbD-driven RP-HPLC method for the simultaneous analysis of dihydropyridines calcium channel blockers in pharmaceuticals // BMC Chemistry. 2025. Vol 19(1). (Q2).
Piponski M., Beneta A., Stefkov G., Karanfilova I.C., Horyn M., Zarivna N. et al. Approaches to the Development of New Simple Rapid HPLC-Photodiode Array Method for the Simultaneous Determination of Levomenthol and Ibuprofen in Gel Pharmaceutical Formulation // Sep Sci plus. 2025. Vol. 8: e70061. (Q3).
Horyn M., Kryskiw L., Kucher T., Zarivna N. et al. Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: application to tablet analysis // BMC Chemistry. 2025. Vol. 19, 8. (Q2).
Halka L., Kucher T., Piponski M., Kryskiw L., Zarivna N. et al. Four ecofriendly spectrophotometric methods for the determination of perindopril through derivatization with sulphophtalein dyes: application to tablet analysis // BMC Chemistry. 2024. Vol. 18. (Q2).
Piponski M., Halka L., Kucher T., Kryskiw L., Horyn M., Zarivna N. et al. Concepts for a new rapid and simple hplc method for simultaneous determination of rosuvastatin and perindopril in dosage forms. // Sep Sci plus. 2024. e202400101. (Q3).
Druchok M., Piponski M., Horyn M., Zarivna N. et al. The usage of salts of chaotropic anions for the development of HPLC method for the simultaneous determination of cisplatin and carboplatin in model mixture // ScienceRise: Pharmaceutical Science. 2025. Vol. 5 (57). P. 29-36. (Q3).

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Education and academic degrees

2026: Award of professional qualification in Analytical and Control Pharmacy, National University of Pharmacy.
2016: Candidate of Pharmaceutical Sciences, specialty 15.00.02 — Pharmaceutical Chemistry and Pharmacognosy, National University of Pharmacy.
2008: Internship in “General Pharmacy”, Ivano-Frankivsk State Medical University.
2007: Faculty of Pharmacy, I. Horbachevsky TSMU.

Positions

Since 2022: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2021–2022: Senior Lecturer, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2018–2021: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2017–2018: Assistant, Department of General Chemistry, I. Horbachevsky TNMU.

Research projects and grants

2024–2026: Investigator on the research project “Development of environmentally safe analytical methods for the determination of APIs from the calcium ion antagonist group in medicinal products” (01240000065).
2023–2026: Investigator on the international project NATO SPS G6031 “Wearable smart patches for multimodal wound healing” (DRESWOUTRE), in cooperation with CNR-IPCB (Italy).
2020–2022: Investigator on the research project “Development of original combinations of antihypertensive agents, their analysis and standardization”.

Professional experience and key skills

Chromatographic and spectrophotometric methods: development, optimization and full validation of HPLC methods (RP-HPLC, HPLC-DAD) and spectrophotometric methods in accordance with ICH, the State Pharmacopoeia of Ukraine, Ph. Eur. and USP.
Design of experiments and statistical processing: application of Quality by Design (QbD) and design of experiments (DoE/RSM, Box-Behnken design). Statistical processing in MS Excel, Origin and Minitab.
Potentiometric titration: acid–base titration in aqueous and non-aqueous media, precipitation and redox titration (Metrohm 888 Titrando automatic titrator).
Green analytical chemistry: assessment of the environmental profile and sustainability of analytical methods using international metrics (AES, AGREE, MOGAPI, AGSA, CACI, CaFRI, BAGI).
Sample preparation: practical experience in solid-phase extraction (SPE) and matrix clean-up.
Peer review: reviewer for Scientific Reports (Q1, Nature Portfolio), BMC Chemistry (Q2) and Separation Science Plus (Q3).

Key publications

Chemical Papers, 2026 (Q2) - https://doi.org/10.1007/s11696-026-04811-8
BMC Chemistry, 2025 (Q2) - https://doi.org/10.1186/s13065-025-01661-5
Separation Science Plus, 2024 (Q3) - https://doi.org/10.1002/sscp.202400101
BMC Chemistry, 2024 (Q2) - https://doi.org/10.1186/s13065-024-01378-x
BMC Chemistry, 2024 (Q2) - https://doi.org/10.1186/s13065-024-01326-9
ScienceRise Pharmaceutical Science, 2024 (Q3) - https://doi.org/10.15587/2519-4852.2024.310564
Science Rise Pharmaceutical Science, 2024 (Q3) - https://doi.org/10.15587/2519-4852.2024.307263
Chemical Papers, 2024 (Q2) - https://doi.org/10.1007/s11696-024-03558-4
ScienceRise Pharmaceutical Science, 2024 (Q3) - https://doi.org/10.15587/2519-4852.2024.302635
Chemical Papers, 2023 (Q2) - https://doi.org/10.1007/s11696-023-03266-5

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Education and academic degrees

2023: Academic title of Associate Professor, Department of Pharmaceutical Chemistry.
2017: Candidate of Pharmaceutical Sciences, specialty 15.00.02 — Pharmaceutical Chemistry and Pharmacognosy.
2011–2013: Faculty of Industrial Pharmacy, National University of Pharmacy.
2004–2006: Faculty of Chemistry and Biology, H. S. Skovoroda Kharkiv National Pedagogical University.
2000–2004: Faculty of Chemistry and Biology, V. Hnatiuk Ternopil National Pedagogical University.

Positions

Since 2021: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2020–2021: Senior Lecturer, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2017–2020: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2004–2017: Senior Laboratory Technician at departments of the National University of Pharmacy (Toxicological Chemistry; Medicinal and Analytical Toxicology).

Research projects and grants

2024–2026: Investigator on the research project “Development of environmentally safe analytical methods for the determination of APIs from the calcium ion antagonist group in medicinal products” (0124U000065).
2023–2026: Investigator on the international project NATO SPS G6031 “Wearable smart patches for multimodal wound healing (DRESWOUTRE)”.
2020–2022: Investigator on the research project “Development of original combinations of antihypertensive agents, their analysis and standardization”.

Professional experience and key skills

Absorption spectrophotometry: development of methods in the UV and visible ranges (including on the Shimadzu UV-1800), and spectrophotometric analysis based on ion-pair complex formation with sulfophthalein dyes.
Pharmaceutical analysis: determination of APIs, impurities and degradation products of ACE inhibitors and statins in substances, dosage forms and biological matrices.
Green analytical chemistry: comprehensive assessment of environmental impact using the Analytical Eco-Scale, AGREE, GAPI and CACI metrics.
Chemical and toxicological analysis: studies of antidiabetic and anticonvulsant phenothiazine derivatives.
Peer review: reviewer for Scientific Reports, BMC Chemistry, Separation Science Plus, Discover Chemistry and Luminescence.
Memberships: co-founder of the NGO “Scientific Society for Pharmaceutical Analytics” (2026); member of the Ukrainian Society for Medicinal Chemistry (since 2025).

Key publications

Mozgova O., Kryskiw L., Kucher T., et al. (2026). Spectrophotometric determination of ethacizine in tablets via oxidative conversion to its sulfone. Chemical Papers. https://doi.org/10.1007/s11696-026-04811-8
Logoyda L., Horyn M., Kryskiw L., Kucher T. et al. (2025). Spectrophotometric determination of nimodipine, nitrendipine, lacidipine in tablets via derivatization with para-dimethylaminobenzaldehyde. ScienceRise: Pharmaceutical Science, 3(55), 30-37.
Horyn M., Kryskiw L., Kucher T. et al. (2025). Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: Application to tablet analysis. BMC Chemistry, 19, 8.
Halka L., Kucher T., Piponski M., Kryskiw L. et al. (2024). Four ecofriendly spectrophotometric methods for the determination of perindopril through derivatization with sulphophtalein dyes. BMC Chemistry, 18, 209.
Halka L., Kucher T., Kryskiw L. et al. (2024). Full green assay of rosuvastatin utilizing sulphophtalein dyes: Application to tablet analysis. ScienceRise: Pharmaceutical Science, 3(49), 4-13.
Kryskiw L., Horyn M., Kucher T. et al. (2024). Novel eco-friendly spectrophotometric determination of lercanidipine hydrochloride in tablets using methyl red. ScienceRise: Pharmaceutical Science, 3(49), 47-53.
Typlynska K., Horyn M., Kucher T. et al. (2024). Two masterful alternative spectrophotometric methods for the determination of ramipril in tablets. ScienceRise: Pharmaceutical Science, 2(48), 44-52.
Mozgova O., Blazheyevskiy M., Kryskiw L., Kucher T. et al. (2024). Determination of prothipendyl by difference spectrophotometric method based on the absorption of its sulfoxide. Chemical Papers.

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Education and academic degrees

2011: Academic title of Associate Professor, Ternopil State Medical University.
2005: Candidate of Pharmaceutical Sciences, specialty 15.00.02 — Pharmaceutical Chemistry and Pharmacognosy, National University of Pharmacy.
2002–2005: Full-time postgraduate study in Pharmaceutical Chemistry and Pharmacognosy, National University of Pharmacy.
1992–1997: Specialty “Industrial Pharmacy” (diploma with distinction), Lviv Polytechnic.

Positions

Since 2019: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2014–2019: Head of the Department of Pharmaceutical Chemistry, I. Horbachevsky TNMU.
2008–2014: Associate Professor, Department of Pharmaceutical Chemistry, I. Horbachevsky TSMU.
2005–2008: Assistant, Department of Pharmaceutical Chemistry, I. Horbachevsky TSMU.
1998–2004: Pharmacist in various pharmacies (“Farmatsiia” state enterprise, “Hryhorii i K” private enterprise) and inspector for organizational and pharmaceutical work.

Research projects and grants

2024–2026: Co-investigator of a research project on the development and validation of analytical and bioanalytical methods for the determination of medicinal products (01240000057).
2024: Co-investigator of a state-funded research project on the development of environmentally safe methods for determining calcium ion antagonists (01240000065).
2020–2022: Responsible investigator of a state-funded research project on the development and standardization of antihypertensive agents (0120U104201).

Professional experience and key skills

Pharmaceutical analysis: ensuring that quality control procedures comply with the requirements of the State Pharmacopoeia of Ukraine, Ph. Eur. and ICH. Rapid analysis of extemporaneous medicinal products.
Potentiometric methods: determination of solution pH and analysis of water content in samples by the Karl Fischer method (using automatic titrators).
Spectrophotometry and TLC: development and validation of methods for the quantification of APIs, and spectral and chromatographic analysis.
Green analytical chemistry: assessment of the greenness of methods using AGREE, ComplexGAPI, MOGAPI and the Eco-Scale.
Statistical data processing: proficiency in Minitab, GraphPad Prism, Microsoft Excel and IBM SPSS.
Memberships: co-founder of the NGO “Scientific Society for Pharmaceutical Analytics” (2026); member of the Ukrainian Society for Medicinal Chemistry (since 2025).

Key publications

Zhuravel A., Piponski M., Kopilevych V., Rezk M., Beneta A., Smachylo I., Zarivna N., Poliak O., Logoyda L. Simultaneous ecofriendly HPLC determination of clotrimazole, miconazole, metronidazole, and lidocaine in pharmaceutical dosage forms. BMC Chemistry. 2026. (Q2)
Horyn M., Kryskiw L., Kucher T., Zarivna N., Poliak O., Logoyda L. Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: application to tablet analysis. BMC Chemistry. 2025. 19(1), 8. (Q2)
Halka L., Kucher T., Kryskiw L., Piponski M., Horyn M., Poliak O. et al. Full green assay of rosuvastatin utilizing sulphophtalein dyes: application to tablet analysis. ScienceRise: Pharmaceutical Science. 2024. 4(50), 4-13. (Q3)
Kryskiw L., Horyn M., Kucher T., Zarivna N., Poliak O., Logoyda L. Novel eco-friendly spectrophotometric determination of lercanidipine hydrochloride in tablets using methyl red. ScienceRise: Pharmaceutical Science. 2024. 3(49), 47-53. (Q3)
Horyn M., Piponski M., Poliak O., Shulyak N., Sulyma M., Logoyda L. Development of the spectrophotometric method for the determination of meldonium in capsules by using alizarine. ScienceRise: Pharmaceutical Science. 2024. 1(47), 12-19. (Q3)
Halka L., Kucher T., Kryskiw L., Piponski M., Furdela I., Uglyar T., Poliak O., Logoyda L. Development of the spectrophotometric method for the determination of rosuvastatin in tablets by using bromophenol blue. ScienceRise: Pharmaceutical Science. 2023. 2(42), 11-19. (Q3)
Shulyak N., Protsyk S., Kucher T., Kryskiw L., Poliak O. et al. Development of the Spectrophotometric Method for the Determination of Atorvastatin Calcium in Tablets by using Bromophenol Blue. Methods and Objects of Chemical Analysis. 2022. 17(3), 111-117. (Q4)
Peleshok K., Piponski M., Ajie E.A., Poliak O. et al. Novel HPLC-UV method for simultaneous determination of valsartan and atenolol in fixed dosage form; Study of green profile assessment. Pharmacia. 2021. 68(1), 43-51. (Q3)

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Education

2025: Department of Epidemiology, Danylo Halytsky Lviv National Medical University, Ukraine.
2002: Clinical Immunology and Microbiology, Kharkiv Medical Academy of Postgraduate Education, Ukraine.
1991: Faculty of Medicine, Ternopil State Medical University, Ukraine.

Positions

2014 – present: Bacteriologist and acting manager of the bacteriological laboratory, Ternopil Regional Clinical Hospital.
2008 – present: Associate Professor, Department of Microbiology, Virology and Immunology, TNMU.
2003 – present: Head of the Microbiology and Parasitology Laboratory, TNMU.
2003–2008: Assistant, Department of Microbiology, Virology and Immunology, TNMU.
1997–2003: Physician, District Hospital in Pidvolochysk, Ternopil region.
1991–1997: Physician, Outpatient Clinic 61615 of a military unit at the city polyclinic in Rustavi, Republic of Georgia.
1983–1985: Orderly, Ternopil Regional Children’s Hospital.

Professional experience and skills

Project management: 2026 RECOOP – CSMC Fusion Research Grant, Project ID #041 RCSS 2026-2028, “Ozonated water and oils as adjunct antimicrobials: sublethal damage, biofilm reduction, and antibiotic synergy” — Co-Investigator (Co-PI).
Supervision: 2024 — supervisor of two qualification theses by students of the Faculty of Pharmacy; 2025 — supervisor of a qualification thesis by a student of the Institute of Pharmacy.
Laboratory methods: microbiological techniques (Gram staining and microscopy; isolation and identification of strains; antimicrobial susceptibility testing according to EUCAST requirements and epidemiological study of MDR; automated identification on VITEK® 2 Compact-15; laboratory diagnosis of borreliosis; record keeping in accordance with ISO 15189:2022).
Academic and teaching competences: teaching “Microbiology, Virology and Immunology”.
Research interests: multidrug resistance of microorganisms, bacterial biofilms, human microbial ecology, and issues in the use of probiotics in medicine.

Key publications

Galaychuk, O. Pokryshko, I. Danylkiv Microbial contamination of ulcerated surface and depth of melanoma invasion / 2nd EACR-AASR-SIC Special conference. 2017. ABSTRACT 601.
Samad, A., Abbas, F., Ahmad, Z., Pokryrshko, O., Asmat, T.M. (2018). Prevalence of Foodborne Pathogens in Food Items in Quetta, Pakistan. Pakistan Journal of Zoology, 50.
Vitaliy Baranovskyi, Ruslan Symchak, Olena Pokryshko, Sergiy Klymnyuk, Bogdan Grishchuk. (2018). Arylsubstituted halogen(thiocyanato)amides containing 4-acetylphenyl fragment. Chem. Chem. Technol., Vol. 12(4):447-450.
Shkilna, M., Andreychyn, M., Korda, M., Pokryshko, O. et al. (2021). Serological Surveillance of Hospitalized Patients for Lyme Borreliosis in Ukraine. Vector borne and zoonotic diseases, 21(4), 301–303.
Tuzyuk, N. V., Pokryshko, O. V. (2022). Microbiological substantiation of the use of xenografts saturated with silver nanocrystals for the treatment of burn wounds. Hospital Surgery. (1), 12–18.
Zaporozhan, S. Y., Fira, D. B., Pokryshko, O. V. (2022). ANTIBACTERIAL THERAPY FOR PATIENTS WITH BURN INJURIES. International Journal of Medicine and Medical Research, 8(1), 18–24.
Natalia Krasij, Sergey Klymnyk, Aleksander Oliynik, Olena Pokryshko. Monitiring of antibiotic susceptibility of microbes isolated from the patients of Ternopil University hospital in 2012 year / Human and health. Volume VII. Issue 4. – 2013. – P. 26-29.
Gasmi A, Shanaida M, Oleshchuk O, Semenova Y, Mujawdiya PK, Pokryshko O et al. (2023). Natural Ingredients to Improve Immunity. Pharmaceuticals, 16(4):528.
Yuzkiv, T. I., Ivakhiv, O. L., Pokryshko, O. V., & Vyshnevska, N. Y. (2023). Epidemiological and clinical features of Lyme borreliosis and its combination with Epstein-Barr virus infection in patients of the Ternopil region. Achievements of Clinical and Experimental Medicine, (2), 142–148.
Pokryshko, O., Khomenko, V. (2023). Experimental translocation of intestinal bacteria caused by closed abdominal trauma, acute blood loss, internal haemorrhage. Bulletin of Medical and Biological Research, 5(2), 15-22.
Pyatkovskyy, T., Pokryshko, O., Bilyk, O., & Danylkov, S. (2024). The use of aqueous ozone solution in the treatment of mine blast injury with extensive soft tissue defects: a case study. International Journal of Medicine and Medical Research, 10(1), 47–55.
Pokryshko, O., Kamyshnyi, O., Tkachuk, N., Oliynyk, N. et al. (2024). The study of intestinal microbiota and duodenal aspirate in patients with giardiasis accompanied by allergic skin diseases. Annals of mechnikov institute, 30–37.
Bjørklund, G., Drapak, I., Zimenkovsky, B., Shanaida, M. et al. (2025). The Role of Vitamins, Magnesium, and Trace Elements in COVID-19 Treatment and Post-COVID-19 Rehabilitation: An Updated Overview. Current medicinal chemistry, 32(16), 3134–3154.
Pyatkovskyy, T., Pokryshko, O., Markowski, A. et al. (2025). Topical ozone application for severe acne with serological evidence of prior varicella-zoster infection after unsuccessful antibiotic and corticosteroid treatment: a case report. J Med Case Reports 19, 337.
Pyatkovskyy T, Pokryshko O. (2025). Antimicrobial activity of ozonated oils and their applications in medicine – a narrative review. Eur J Clin Exp Med;23 (2):512–517.
Dovgalyuk A, Levkiv M, Dudkevych O, Pokryshko O. (2025). Antimicrobial properties of mesenchymal stem cells: prospects for application against antibiotic-resistant infections. Cell Organ Transpl. 13(2):e2025132185.
Olena Pokryshko, Taras Pyatkovskyy. (2025). Alcohol-based hand sanitizers in Ukraine: a comparative evaluation of their effectiveness. Журнал «Перспективи та інновації науки», 6(52):1683-1693.
Pokryshko O.V., Filiminova N.I., Klymniuk S.I. Local monitoring of antibiotic susceptibility of uropathogenic bacteria conducted in 2024. Матеріали XVI з’їзду Товариства мікробіологів України імені С.Виноградського, 2025. С. 223.
Yashan O, Pokryshko O, Krasii N, Yashan A, Buchynskyj P, Buchko O. (2025). Features of diagnosis of diffuse otitis externa and treatment with the combined drug “Candibiotik”. Otorhinolaryngology. 3-4(8).

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Education

2023: Master’s degree in Biology, Ivan Franko National University of Lviv.
2001: Specialist degree in “Pedagogy and Methods of Secondary Education. Biology and Chemistry”, V. Hnatiuk Ternopil National Pedagogical University.

Positions

2013 – present: Associate Professor, I. Horbachevsky TNMU, Ministry of Health of Ukraine.

Professional experience and skills

Project management: 2026 RECOOP – CSMC Fusion Research Grant, Project ID #041 RCSS 2026-2028, “Ozonated water and oils as adjunct antimicrobials: sublethal damage, biofilm reduction, and antibiotic synergy” — Co-Investigator (Co-PI).
Professional experience: professional traineeship under the “Erasmus+ KA107 Teaching Staff Mobility” program at the University of Santiago de Compostela (2026); FEMS Summer School for Postdocs 2021 at MedILS in Split (2022); traineeship at the Department of Microbiology, Wroclaw Medical University (2017); advanced training in Bacteriology at the P. L. Shupyk National Medical Academy of Postgraduate Education (2015).
Specialized microbiological research and biofilm formation: study of bacterial biofilm formation, detection and analysis of genetic markers of biofilm formation. Practical experience in determining the susceptibility and resistance of microorganisms to antiseptics; determination of MIC/MBC.
Scientific expertise and peer review: experience in reviewing research papers and master’s theses; preparation and systematization of data for publications.

Key publications

Kravets, N., Klymnyuk, S., Romanyuk, L., Borak, V., & Mykhailyshyn, H. (2020). Investigation of strains of microorganisms isolated from children with recurrent tonsillitis. Georgian Medical News, (298), 49–53.
Kravets, N. Ya., Klumnyk, S. I., Romanyuk, L. B., & Borak, V. P. (2022). Biofilm-forming properties of pathogenic micro-organisms in children with recurrent tonsillitis. Світ медицини та біології, (2)(80), 210–213.
Romanyuk, L. B., Klumnyuk, S. I., Mykhailyshyn, H. I., Volch, I. R., & Kravets, N. Ya. (2022). Retrospective Analysis of Antibiotic Therapy and Sensitivity to Antifungals of Fungi of the Genus Candida, Secreted from Patients with Viral-Bacterial Pneumonia Associated with COVID-19. Mikrobiolohichnyi Zhurnal, 84(1), 15–19.
Romanyuk, L., Malinovska, L., Kravets, N., Olyinyk, N., & Volch, I. (2022). Analysis of antibiotic resistance of conditionally pathogenic ortopharyngeal microflora in children after viral respiratoty infections. Georgian Medical News, (7)(328), 154–157.
Kravets, N., Malinovska, L., & Romanyuk, L. (2024). Utilizing the dominance index to evaluate microbial contamination on pharmacy room displays. Health Problems of Civilization, 8(4), 474–480.
Kravets, N., Shevchyk, L., Hrod, I., Romanyuk, L., & Klumnyuk, S. (2025). Ecological characteristics of the soft plaque microbiome: Influence of external factors and biodiversity indexes. Mikrobiolohichnyi Zhurnal, 87(2), 85–95.
Volch, I., Mykhailyshyn, H., Kravets, N., Pyatkovskyy, T., & Bukata, V. (2025). Biofilm formation and antibiotic resistance of clinical isolates from diabetic foot ulcers. Bulletin of Medical and Biological Research, 7(3), 46–53.
Кравець, Н., & Олійник, Н. (2025). Антибактеріальна ефективність рослинних препаратів та протеїнату срібла щодо збудників гострого тонзиліту (Streptococcus spp. і Staphylococcus aureus). Фітотерапія. Часопис, (3), 62–68.
Кравець Н., Драпак О., Черняшова В. (2026). Вплив антибіотикотерапії в анамнезі на формування клінічного перебігу гострого тонзиліту та стану ротоглоткової мікробіоти. Фітотерапія. Часопис, 1, 91–100.

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Education

1998: Faculty of Medicine, I. Horbachevsky Ternopil State Medical Academy, specialty General Medicine.

Positions

2013–2026: Associate Professor, Department of Microbiology, Virology and Immunology, TNMU.
2006: Assistant, Department of Microbiology, Virology and Immunology, TNMU.

Professional experience and skills

Project management: 2019–2021 “Monitoring of antibiotic-resistant strains in somatic and infectious pathology in people of different ages” (responsible investigator) — research project.
Other professional experience: supervisor of a qualification thesis by a student of the Institute of Pharmacy (2026); supervisor of two qualification theses by students of the Faculty of Pharmacy (2024).
Clinical and applied medical skills: clinical practice in pediatrics; translation of evidence-based research on infectious diseases into clinical pediatric protocols.
Academic and teaching competences: teaching microbiology, virology and immunology; preparation of papers for international peer-reviewed journals.

Key publications

Barna O, Aponchuk N, Romanyuk L, Hrabovets M, Fedorovska M, & Shanaida M. (2026) Optimal Method Selection for Extracting Bioactive Compounds from Prunus spinosa L. Fruits and Evaluating the Antimicrobial Activity of the Resulting Extract. Biomedical & Pharmacology Journal, March 2026. Vol. 19(1) Р. 738-751.
Климнюк, С.І., Романюк, Л.Б., & Ткачук, Н.І. (2026) Відчуття кворуму бактерій, як спосіб їх комунікації у біоплівках. Журнал «Інфекційні хвороби» 1 (123), 46 -55.
Покришко, О. В., Копча, В. С., Пятковський, Т. І., Михайлишин, Г. І., Олійник, Н. М., & Романюк, Л. Б. (2025). Технічні методи реєстрації підозрілих спалахів інфекційних захворювань, що вимагають розслідування. Журнал «Вісник соціальної гігієни та організації охорони здоров’я України», 3 (105), 190–195.
Климнюк, С.І., & Романюк, Л.Б. (2025) Пробіотики в медицині: від минулого до сьогодення. Журнал «Інфекційні хвороби» 4 (122), 4 -20.
Маліновська, Л. І., Бегош, І. Б., Романюк, Л. Б., & Бегош, Н. Б. (2025) Мікробіом шкіри нижніх кінцівок і діабетична виразка стопи: погляд на проблему. Журнал «Здобутки клінічної і експериментальної медицини» 4 (додаток), 147-153.
Futujma, Y.M., Malinovska, L.I., Krasii, N.I., & Romanyuk, L.B. (2025) Microbial Profile Of The Wound Surface In Mine-Explosive Injuries. International Scientific Periodical Journal "SWorldJournal", Issue No34 Part 5. 81-86.
Kravets, N., Shevchyk, L., Grod, I., Romanyuk, L., & Klumnyuk, S. (2025). Ecological Characteristics of the Soft Plaque Microbiome: Influence of External Factors and Biodiversity Indexes. Mikrobiolohichnyi Zhurnal, 87(2), 85–95.
Маліновська Л. І., Марчишин С. І., Романюк Л. Б. (2024). Роль мікробної контамінації вітрин аптеки у виникненні респіраторної патології. Перспективи та інновації науки, 3(37), 1348–1358.
Romanyuk, L. B., Klumnyuk, S. I., Mykhailyshyn, H. I., Volch, I. R., & Kravets, N. Y. (2022). Retrospective Analysis of Antibiotic Therapy and Sensitivity to Antifungals of Fungi of the Genus Candida, Secreted from Patients with Viral-Bacterial Pneumonia Associated with COVID-19. Mikrobiol. Z., 84(1), 15–19.
Zahrychuk, O. M., Mykhailyshyn, H. I., Volch, I. R., Klumnyuk, S. I., & Romanyuk, L. B. (2023). Species Characteristics of Causative Agents of Acute Appendicitis in Children and Determination. Mikrobiol. Z., (3), 22–31.
Kravets, N. Y., Klumnyk, S. I., Romanyuk, L. B., & Borak, V. P. (2022). Biofilm-forming properties of pathogenic micro-organisms in children with recurrent tonsillitis. Світ медицини та біології, 2(80), 210–213.
Romanyuk, L., Malinovska, L., Kravets, N., Olyinyk, N., & Volch, I. (2022). Analysis of antibiotic resistance of conditionally pathogenic ortopharyngeal microflora in children after viral respiratoty infections. Georgian medical new, (7)328, 154–157.
Kravets, N., Klymnyuk, S., Romanyuk, L., Borak, V., & Mykhailyshyn, H. (2020). Investigation of strains of microorganisms isolated from children with recurrent tonsillitis. Georgian Med News, (298), 49–53.
Волянська Л. А., Бурбела Е. І., Романюк Л. Б. (2019). Неконтрольованість кору в епоху керованих інфекцій. Здоровье ребенка, 14(4), 242–249.
Волянська Л. А., Романюк Л. Б., Бурбела Е. І., Горішна І. Л. (2019). Мікробіота ротоглотки в дітей у період висипання кору. Актуальна інфектологія, 7(3), 150–154.
Романюк Л. Б., Климнюк С. І., Кравець Н. Я., Копча В. С., Дронова О. Я. (2019). Антибіотикорезистентність умовно-патогенних мікроорганізмів: актуальність, умови виникнення, шляхи подолання. Інфекційні хвороби, (4), 63–70.

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Education

2007–2012: Volodymyr Hnatiuk Ternopil National Pedagogical University, Faculty of Chemistry and Biology, specialty “Biology”.

Positions

2016 – present: Associate Professor, Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University, Ministry of Health of Ukraine.

Professional experience and skills

Project management: 2026 RECOOP – CSMC Fusion Research Grant, Project ID #041 RCSS 2026-2028, “Ozonated water and oils as adjunct antimicrobials: sublethal damage, biofilm reduction, and antibiotic synergy” — Co-Investigator (Co-PI).
Molecular biology and laboratory methods: practical experience: quantitative real-time polymerase chain reaction (RT-qPCR) and Western blot analysis.
Academic and teaching competences: teaching microbiology, virology and immunology; participation in international grant projects; preparation of papers for international peer-reviewed journals.

Key publications

Volch, I., Mykhailyshyn, H., Kravets, N., Pyatkovskyy, T., & Bukata, V. (2025). Biofilm formation and antibiotic resistance of clinical isolates from diabetic foot ulcers. Bulletin of Medical and Biological Research, 7(3), 46-53.
Волч, І. Р., Подобівський, С. С. (2025). Аналіз поширення кліщів Ixodes ricinus і Dermacentor reticulatus у деяких природних екосистемах Тернопільської області. Здобутки клінічної і експериментальної медицини, (2), 45–50.
Pokotylo O, Volch I, Mykhailyshyn H, Demchuk M, Dub A. Pharmacoeconomic evaluation of pharmacotherapy of patients with diabetic foot syndrome secondary to type 2 diabetes mellitus. Int J Med Med Res. 2025;11(2):120–130.
Volch, Iryna, Mykhailyshyn, H., Pokotylo, O., Hetman, U., & Bukata, V. (2024). Microbiological analysis of wound content in patients with type 2 diabetes mellitus with diabetic foot syndrome. International Journal of Medicine and Medical Research, 10(1), 6-14.
Zahrychuk, O., Mykhailyshyn, H., Volch, I., Klumnyuk, S., & Romanyuk, L. (2023). Species Characteristics of Causative Agents of Acute Appendicitis in Children and Determination of Their Susceptibility to Antibiotics. Mikrobiolohichnyi Zhurnal, 85(3), 22–31.

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Education

2024: PhD in specialty 091 “Biology”, field of knowledge 09 “Biology”.
2023: Awarded a specialist certificate in “Microbiology”.
1999: Kamianets-Podilskyi State Pedagogical University, full higher education in “Primary Education, Pedagogy and Methods of Secondary Education, Biology”.

Positions

2025: Associate Professor, Department of Microbiology, Virology and Immunology.
2018–2025: Assistant, Department of Microbiology, Virology and Immunology.

Professional experience

Project management: 2026 RECOOP – CSMC Fusion Research Grant, Project ID #041 RCSS 2026–2028, “Ozonated water and oils as adjunct antimicrobials: sublethal damage, biofilm reduction, and antibiotic synergy” — Co-Investigator (Co-PI).

Key publications

Pokotylo, O., Volch, Iryna, Mykhailyshyn, H., Demchuk, M., & Dub, A. (2025). Pharmacoeconomic evaluation of pharmacotherapy of patients with diabetic foot syndrome secondary to type 2 diabetes mellitus. International Journal of Medicine and Medical Research, 11(2), 120-130.
Voroniuk, Y., Antonova-Rafi, Y., & Mykhailyshyn, H. (2025). Differential diagnosis of grip strength development in individuals with occupational and pathological hypermobility: a pilot study. Rehabilitation and Recreation, 19(1), 171–178.
Volch, I., Mykhailyshyn, H., Kravets, N., Pyatkovskyy, T., & Bukata, V. (2025). Biofilm formation and antibiotic resistance of clinical isolates from diabetic foot ulcers. Bulletin of Medical and Biological Research, 7(3), 46–53.
Kovalchuk, V., Reva, S., Volch, I., Shcherbyna, S., Mykhailyshyn, H., & Lychova, T. (2025). Artificial intelligence as an effective tool for personalized learning in modern education. ETR, 3, 187–194.
Zahrychuk, O. M., Mykhailyshyn, H. I., Volch, I. R., Klumnyuk, S. I., & Romanyuk, L. B. (2023). Species Characteristics of Causative Agents of Acute Appendicitis in Children and Determination. Mikrobiol. Z., (3), 22–31.
Mykhailyshyn, H. I., Klumnyuk, S. I., Spivak, M. Ya., Sverstiuk, A. S., & Lazarenko, L. M. (2023). The Effect of Probiotic Therapy on the Vagina Microbiota and the Humoral Link of Immunity in Bacterial Vaginosis. Mikrobiol. Z., (3), 32–47.
Romanyuk, L. B., Klumnyuk, S. I., Mykhailyshyn, H. I., Volch, I. R., & Kravets, N. Ya. (2022). Retrospective Analysis of Antibiotic Therapy and Sensitivity to Antifungals of Fungi of the Genus Candida, Secreted from Patients with Viral-Bacterial Pneumonia Associated with COVID-19. Mikrobiol. Z., 84(1), 15–19.
Михайлишин, Г. І. (2023). Вплив бактерійного вагінозу на розвиток порушень клітинної ланки імунітету у жінок репродуктивного віку. Інфекційні хвороби, (4), 52–57.
Михайлишин, Г. І. (2023). Аналіз т-клітинної ланки імунітету в жінок з порушенням мікробіоти вагіни під впливом комплексного лікування. Медична та клінічна хімія, 25(3), 144–150.

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Education

2004: Higher education, V. Hnatiuk Ternopil State Pedagogical University, Ukraine.

Positions

2022 – present: Acting Head of the Central Research Laboratory, I. Horbachevsky TNMU, Ukraine.
2013–2022: Senior Researcher, Central Research Laboratory, I. Horbachevsky TSMU, Ukraine.
2010–2013: Researcher, Central Research Laboratory, I. Horbachevsky TSMU, Ukraine.
2005–2010: Junior Researcher, Central Research Laboratory, I. Horbachevsky TSMU, Ukraine.

Project management experience (2005–2021)

Correction of structural and functional changes in the small intestine in combined pathologies of the pancreato-hepatobiliary organs using biospecific selective immunosorbents and magnetic laser radiation (experimental study). — biochemical and immunological testing. Funded by the Ministry of Health of Ukraine.
Study of the morphological condition of the kidney and large joints in combined pathologies of the pancreato-hepatobiliary organs. — responsible investigator. Funded by the Ministry of Health of Ukraine.
Structural and metabolic changes in the cerebral cortex, kidneys and liver caused by chronic neoplastic intoxication and components of cytostatic therapy, and their correction by sorption. — responsible investigator. Funded by the Ministry of Health of Ukraine.
Morphofunctional state of the spleen and factors of immunological reactivity under conditions of experimental carcinogenesis. — responsible investigator. Funded by the Ministry of Health of Ukraine.
Immunogenetics of malignant growth: the influence of BCL-2 gene expression on antitumor immunity and under the corrective influence of nanomaterials. — responsible investigator. Funded by the Ministry of Health of Ukraine.

Key research and professional skills

Statistical analysis and data processing; performing advanced statistical analysis of research data sets.
Biochemical and enzyme immunoassay studies. Practical experience with modern experimental equipment.

Key publications

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Education

2026: PhD (specialty 222 Medicine) — Department of Microbiology, Virology and Immunology, I. Horbachevsky Ternopil National Medical University.
2020: Master of Medicine (MD) — Faculty of Medicine, I. Horbachevsky Ternopil National Medical University.

Positions — current and previous

2026 – present: Junior Researcher — I. Horbachevsky Ternopil National Medical University, Ministry of Health of Ukraine.
2022–2026: PhD candidate (specialty 222 Medicine) — Department of Microbiology, Virology and Immunology, TNMU.
2024–2025: Visiting researcher (Erasmus+ KA107 mobility project) — Paul Sabatier University (Toulouse), France.
2020–2022: Resident physician (Internal Medicine) — I. Horbachevsky Ternopil National Medical University / university clinical bases.

Project management experience

2023: Participant in the RECOOP HST Association project “Comprehensive Analysis of Genetic Predictors for MAFLD Development in Patients with COVID-19” (Grant #36 – CSMC Senior Scientists), funded by Cedars-Sinai Medical Center / RECOOP.

Other relevant professional experience

2026: Training under the WHO mhGAP (Mental Health Gap Action Program) — certified provider of mental health services in non-specialized health care settings.
2024–2025: Erasmus+ KA107 “Mobility Project for Higher Education Students and Staff” at Paul Sabatier University (Toulouse, France). Carried out an experimental research project on the molecular genetic mechanisms of cardiovascular aging and metabolic remodeling. Mastered modern molecular biology methods (RT-qPCR, Western blot) and digital histological analysis (QuPath).
2022–2026: Postgraduate teaching assistant for “Microbiology, Virology and Immunology” for second- and third-year medical students at TNMU.

Key research and professional skills

Statistical analysis and data processing: advanced statistical analysis of research data sets, including linear/non-linear regression and mixed-effects models. Works in GraphPad Prism, JASP and Jamovi.
Molecular biology and laboratory methods: practical experience: quantitative real-time polymerase chain reaction (RT-qPCR) and Western blot analysis.
Digital pathology: digital histological analysis using QuPath software for precise quantitative tissue assessment.
Clinical and applied medical skills: clinical practice in internal medicine, translation of evidence-based research on infectious diseases into clinical treatment protocols, and provision of mental health services in non-specialized health care settings (WHO mhGAP certificate).
Academic and teaching competences: teaching microbiology, virology and immunology; participation in international grant projects; preparation of papers for international peer-reviewed journals.

Invited presentations at international peer-reviewed conferences

The role of host genetics in modulating COVID-19 response to Paxlovid treatment. 20th RECOOP Bridges in Life Sciences Conference, Prague, April 2025.
Impact of Paxlovid Treatment on Clinical Outcomes in COVID-19 Patients with Metabolic-Associated Fatty Liver Disease. 19th RECOOP Bridges in Life Sciences Conference, Bratislava, April 2024.

Main publications

Buchynskyi M, Kamyshna I, Lyubomirskaya K, Moshynets O, Kobyliak N, Oksenych V, Kamyshnyi A. Efficacy of interferon alpha for the treatment of hospitalized patients with COVID-19: A meta-analysis. Front Immunol. 2023; 14:1069894.
Buchynskyi M, Oksenych V, Kamyshna I, Kamyshnyi O. Exploring Paxlovid Efficacy in COVID-19 Patients with MAFLD: Insights from a Single-Center Prospective Cohort Study. Viruses. 2024; 16(1):112. (Q1).
Buchynskyi M, Oksenych V, Kamyshna I, Vorobets I, Halabitska I, Kamyshnyi O. Modulatory Roles of AHR, FFAR2, FXR, and TGR5 Gene Expression in Metabolic-Associated Fatty Liver Disease and COVID-19 Outcomes. Viruses. 2024; 16(6):985.
Buchynskyi M, Oksenych V, Kamyshna I, Budarna O, Halabitska I, Petakh P, Kamyshnyi O. Genomic insight into COVID-19 severity in MAFLD patients: a single-center prospective cohort study. Front Genet. 2024; 15:1460318. (Q2).
Buchynskyi M, Kamyshna I, Halabitska I, Petakh P, Oksenych V, Kamyshnyi O. Genetic Predictors of Paxlovid Treatment Response: The Role of IFNAR2, OAS1, OAS3, and ACE2 in COVID-19 Clinical Course. J Pers Med. 2025; 15(4):156.
Kamyshnyi A, Koval H, Kobevko O, Buchynskyi M, Oksenych V, Kainov D, Lyubomirskaya K, Kamyshna I, Potters G, Moshynets O. Therapeutic Effectiveness of Interferon-α2b against COVID-19 with Community-Acquired Pneumonia: The Ukrainian Experience. Int J Mol Sci. 2023; 24(8):6887.
Buchynskyi M, Kamyshna I, Oksenych V, Zavidniuk N, Kamyshnyi A. The Intersection of COVID-19 and Metabolic-Associated Fatty Liver Disease: An Overview of the Current Evidence. Viruses. 2023; 15(5):1072.
Buchynskyi M, Oksenych V, Kamyshna I, Vari SG, Kamyshnyi A. Genetic Predictors of Comorbid Course of COVID-19 and MAFLD: A Comprehensive Analysis. Viruses. 2023; 15(8):1724.
Buchynskyi M, Kamyshna I, Halabitska I, Petakh P, Kunduzova O, Oksenych V, Kamyshnyi O. Unlocking the gut-liver axis: microbial contributions to the pathogenesis of metabolic-associated fatty liver disease. Front Microbiol. 2025; 16:1577724.
Halabitska I, Petakh P, Buchynskyi M, Kamyshna I, Lushchak O, Kamyshnyi O. War, diet, and PTSD in Ukrainian youth. Sci Rep. 2025 Dec 4;16(1):1422. doi: 10.1038/s41598-025-31138-3.
Halabitska I, Buchynskyi M, Kamyshna I, Petakh P, Lushchak O, Kamyshnyi O. Six-month statin therapy and short-term MASLD progression: a prospective cohort study adjusted for abdominal obesity and glycemic control. Sci Rep. 2026 Jun 30. doi: 10.1038/s41598-026-59298-w.

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Education

2000: Postgraduate study, Faculty of Biology — Taras Shevchenko National University of Kyiv. Specialty: cytology, cell biology, histology. Candidate of Biological Sciences.
1994: Faculty of Chemistry and Biology, Ternopil State Pedagogical Institute. Specialty: biology and chemistry.

Positions

2009 – present: Associate Professor, Department of Histology and Embryology — I. Horbachevsky Ternopil National Medical University.
2004–2009: Assistant, Department of Histology and Embryology — I. Horbachevsky Ternopil National Medical University.
2000–2004: Leading Engineer, Department of Plant Ecomorphogenesis — Institute of Ecology of the Carpathians, National Academy of Sciences of Ukraine, Lviv.

Project management experience

2024–2026: Responsible investigator of the research project “Study of the corrective effect of mesenchymal stem cells on the regeneration of damaged tissues in an experimental model” (state registration No. 0124U100058).
2024–2025: Responsible investigator of the state-funded research project “Application of regenerative medicine technologies for the treatment of chronic wounds” (state registration No. 0124U001099).
2021–2025: Supervisor of the dissertation of Ilona Palii, “Structural and functional changes of the kidneys in experimental acute respiratory distress syndrome and its correction with mesenchymal stem cells”.
2020–2024: Supervisor of the dissertation of Olesia Redko, “Morphofunctional state of the liver in acute respiratory distress syndrome and under its correction with mesenchymal stem cells”.
2021–2023: Responsible investigator of the state-funded research project “Study of the regenerative potential of cell therapy agents in acute respiratory distress syndrome” (state registration No. 0121U100159).
2020–2022: Responsible investigator of the interdepartmental research project “Study of the regenerative potential of mesenchymal stem cells in experimental tissue damage and the prospects for their therapeutic use” (state registration No. 0120U104146).

Other relevant professional experience

2026–2027: Participant/investigator in the international grant study “MSC-Derived Extracellular Vesicles as a Cell-Free Therapy for Burn Injuries”, funded by the Seed Funding Twinning Initiative under the Ukrainian–British partnership.
2023: Professional research traineeship in biotechnology and cell cultures under the Erasmus+ KA1 Mobility for Training program at Aristotle University (Thessaloniki, Greece).

Key research and professional skills

Cell biology and laboratory methods: practical experience: in vitro stem cell culture, immunophenotyping and karyotyping of cell lines, exosome isolation, enzyme immunoassay, immunohistochemical and immunofluorescence analyses, morphometry and electron microscopy.
Academic and teaching competences: 22 years of experience teaching histology, cytology and embryology in Ukrainian and English. Development of syllabuses, creation of teaching materials and delivery of the elective courses “Cell Technologies in Medicine” and “Biotechnologies Using Stem Cells”. Collaboration within international grant projects.
Memberships: Scientific Society of Anatomists, Histologists, Embryologists and Topographic Anatomists of Ukraine (since 2004).
WHO certification: mhGAP training program (2024–2025) “Management of common mental disorders in primary health care”.

Research output and key publications

Author of 129 scientific and educational publications, including 47 research papers in specialized Ukrainian and international journals.

Dovhaliuk AI; Kulianda OI; Ohinska NV; Redko OS; Kulianda OO; Kovalchuk AO; Kulbitska VV; Kramar SB; Korda MM; Shevchuk OO. Acellular dermal matrix for chronic wound treatment: dry or wet? Ukr.Biochem.J. 2026; 98(4): 108-126. https://doi.org/10.15407/ubj98.04.108
Dovgalyuk A, Levkiv M, Dudkevych O, Pokryshko O. Antimicrobial properties of mesenchymal stem cells: prospects for application against antibiotic-resistant infections. Cell Organ Transpl. 2025; 13(2):e2025132185. https://doi.org/10.22494/cot.v13-2.185
Mekhno NYa, Dovgalyuk AI, Tokarskyy OS, Korda MM, Yaremchuk OZ. (). L-arginine, aminoguanidine and mesenchymal stem cells reduce the level of endoplasmic reticulum stress markers and D-dimer in the lungs of mice with antiphospholipid syndrome. Ukr.Biochem.J., 2024; 96(5), 21–30. https://doi.org/10.15407/ubj96.05.021
Mekhno N, Dovgalyuk A, Kulitska M, Hlyvka N, Dutchak O, Kornaga S, Korda M, Yaremchuk O. Human umbilical cord-derived mesenchymal stem cells and nitric oxide synthase modulators inhibit apoptosis and activate autophagy in the lungs of mice with an antiphospholipid syndrome model. Cell Organ Transpl. 2024; 12(2):94-101 (e2024122168). https://doi.org/10.22494/cot.v12i2.168
Palii I, Dovgalyuk A, Kramar S, Korda M. Changes in the macrophage polarization in the kidneys of rats with acute respiratory distress syndrome after transplantation of human umbilical cord-derived mesenchymal stem cell. Cell Organ Transpl. 2024; 12(2):102-109 (e2024122170). https://doi.org/10.22494/cot.v12i2.170
Varvaruk M-I, Dovgalyuk A, Dzubanovsky I, Holovata T, Shevchuk O. The effect of human umbilical cord-derived mesenchymal stem cell transplantation on reparative processes during the reconstruction of muscle-aponeurotic defects of the anterior abdominal wall in rats. Cell Organ Transpl. 2024; 12(2):110-117 (e2024122171). https://doi.org/10.22494/cot.v12i2.171
Palii I, Dovgalyuk A, Redko O, Dovbush A, Kramar S, Nebesna Z, Korda M. Morphofunctional changes in the kidneys of rats during acute respiratory distress syndrome and its treatment with human umbilical cord-derived mesenchymal stem cells // Cell Organ Transpl. 2024; 12(1): 60-71. https://doi.org/10.22494/cot.v12i1.166
Mekhno N, Dovgalyuk A, Korda M, Yaremchuk O. Human umbilical cord-derived mesenchymal stem cells and nitric oxide modulators attenuate the proinflammatory cytokine pattern in experimental antiphospholipid syndrome in mice // Cell Organ Transpl. 2024; 12(1): 44-50. https://doi.org/10.22494/cot.v12i1.163
Redko O, Dovgalyuk A, Kramar S, Ohinska N, Nebesna Z, Korda M. Mesenchymal stem cell therapy modulates macrophage dynamics in ARDS-associated liver injury in rats // Cell Organ Transpl. 2023; 11(2): 34-45. https://doi.org/10.22494/cot.v11i2.157
Redko O., Dovgalyuk A., Kramar S., Nebesna Z., Sverstyuk A., Korda M. Human umbilical cord-derived mesenchymal stromal cells mitigate LPS-induced liver injury in rats. Cell Organ Transpl. 2023; 11(1): 34-45. https://doi.org/10.22494/cot.v11i1.148

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Education

2020: Postgraduate study (PhD), I. Horbachevsky Ternopil National Medical University. Dissertation: “Optimization of methods for studying vector-borne infections transmitted by ticks and mosquitoes”.
2010: Postgraduate specialization in “Virology”, P. L. Shupyk National Medical Academy of Postgraduate Education, Kyiv.
2007: Diploma, V. Hnatiuk Ternopil National Pedagogical University.
1988: Diploma, Zhytomyr Special Medical College.

Professional experience

2023 – present: PhD candidate, I. Horbachevsky Ternopil National Medical University.
2017 – present: Lead Specialist of the ILC (virologist of the highest qualification category), Head of the PCR Unit, I. Horbachevsky TNMU.
2014–2016: Interdepartmental Teaching and Research Laboratory, I. Horbachevsky TSMU.
2011: Lead Specialist (virologist), Interdepartmental Research Laboratory, I. Horbachevsky TSMU.
2002–2014: Interdepartmental Research Laboratory, I. Horbachevsky TSMU.
1993–2002: Emergency laboratory assistant for intensive care and resuscitation units, City Hospital No. 2, Ternopil.
1990–1993: Laboratory assistant, Regional Pathology Bureau, Zhytomyr.

Traineeships and specialized training

2018: Traineeship at the Institute of Rural Health, Lublin, Poland.
2018–2025: Participation in numerous academic and practical seminars, webinars and training courses, including “Innovations in Cell Biology”, “CRISPR-Cas9 Genome Editing”, “PCR in the Diagnosis of COVID-19”, “Current Infectious Diseases”, “Laboratory Diagnosis of Human Papillomaviruses”, “Blood Groups and the Rh Factor” and others.

Key publications

Marchuk O.M., Podobivsky S.S. Multiplex research format as an optimization of the process of the method for determining pathogens of vector – borne infections amound ticks and mousquito populations // Summary LXIX Scientific and Practical «Achievements of clinical and experimental medicine»/ (11-12 June). – 2026.
Marchuk O.M., Volch I.R. Multiplex system for the detection of patogens of transmissible infections // Summary LXIX Scientific and Practical «Achievements of clinical and experimental medicine»/ (11-12 June). – 2026.
Podobivsky S.S., Marchuk O.M. Ticks-borne infections – a threat to human health in the Ternopil region // Scientific and practical internet conference with international participation «Modern problems of studying medical and ecological aspects of human health» / Poltava (23-24 October). – 2025. – P. 302–303.
Podobivsky S.S., Fedonyuk L. Y., Andreychyn M. A., Marchuk O. M., Pavlyuk T. V. Pathogens of human and animal infectious diseases and their spread in Europe by the ixodid tick Dermacentor reticulatus // Mikrobiolohichnyi Zhurnal.- 2023. Vol.85 (6). P. 106–117.
Nykytyuk S., Klymnyuk S., Panichev V., Marchyk O., Klyshch I. Experience of PCR on Lyme borreliosis in children from the Ternopil region // Family Medicine & Primary Care Review. – 2022. Vol. 24 (4). – P. 1-2.
Marchuk O.M. Features of research on ticks and mosquitoes in the spread of transmissible infections // Proceedings of the All-Ukrainian scientific and practical conference with international participation "Environmental and biological education in the concept of 'One Health'". – Ternopil (April 27-29). – 2022. – P. 53-54.
Marchuk O.M., Podobivskyi S.S., Fedonyuk L.Ya. Optimization of research on transmissible infections transmitted by ticks and mosquitoes // Scientific notes of Ternopil National Pedagogical University named after Volodymyr Hnatyuk. Series "Biology". – 2021. – No. 3 (81). - P. 33-39.
Andreychyn M.A., Korda M.M., Shkilna M.I., Ivakhiv O.L. etc. // Lyme-borreliosis: monograph. - Ternopil. – 2021. – P. 268-297.
Fedoniuk L. Ya., Podobivskiy S. S., Pryvrotska I. B., Miklashevska O. A., Marchuk O. M. The results of the study of the epidemiological status and spread of Dermacentor Reticulatus ticks in Ukraine over the last 10 years // Wiadomości Lekarskie. – 2021. – Vol. 74 (8). – P. 1952-1959.
Marchuk O.M., Podobivskyi S.S., Fedoniuk L.Ya. Research of infections transmitted by ticks and mosquitoes and directions of their optimization // Мат-ли науково-практичної конференції з міжнародною участю «Лінгводидактика в контексті особистісної парадигми», м. Тернопіль (3-4 червня). – 2021. – P. 53-54.
Fedoniuk L.Ya., Podobivskyi S.S., Kamyshnyi A.M., Saturska A.S., Khavtur V.O., Marchuk O.M., Zahrychuk O.M., Furka O.B., Cherniashova V.M. Morphological and physiological, biological and epidemiological features of acariana of the genus Ixodes (Latreille, 1795) - human ectoparasites in biogeocenoses of Ternopil region // Wiadomości Lekarskie. – 2019. – TOM LXXII, no 2. – P. 224–228.
Podobivskyi S.S., Marchuk O.M., Fedoniuk L. Ja., Vakirjak N. P., Podobivskyi W.S., Furka L.B., Jarema O.M. Comparative characteristic of the morpho-physiological parameters biology and epidemiology of ixodidae (Ixodes and Dermacentor) // Deutscher Wissenschaftsherold. – 2018 – no. 2. – P. 10-12.
Andreychyn M.A., Shkilna M.I., Nikityuk S.O., Podobivskyi S.S., Marchuk O.M., Klishch I.M., Korda M.M. The frequency of detection of Borrelia and Anaplasma in ticks removed from residents of the Ternopil region // Proceedings of the All-Ukrainian Scientific and Practical Conference of Infectious Disease Specialists and the Plenum of the All-Ukrainian Association of Infectious Disease Specialists. - Zhytomyr - 2017. – P. 9-10.

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Education

2016: Doctor of Biological Sciences, I. Horbachevsky TNMU.
2009: Candidate of Biological Sciences, I. Horbachevsky TNMU.
2003: Faculty of Chemistry and Biology, Volodymyr Hnatiuk Ternopil State Pedagogical University.

Positions

2019 – present: Head of the Department of Histology and Embryology, TNMU.
2016 – present: Director of the Educational and Research Institute of Morphology, TNMU.
2017–2019: Professor, Department of Histology and Embryology, TNMU.
2013–2017: Associate Professor, Department of Histology and Embryology, TNMU.
2011–2013: Senior Lecturer, Department of Histology and Embryology, TNMU.
2008–2011: Assistant, Department of Histology and Embryology, TNMU.

Project management experience (grants and research projects)

2026–2028: Scientific supervisor of the research project “Features of structural and metabolic changes in tissues and organs of experimental animals in pathological conditions of various origins” (No. 0126U000030).
2024–2025: Investigator on the state-funded research project “Application of regenerative medicine technologies for the treatment of chronic wounds” (No. 0124U001099).
2023–2025: Scientific supervisor of the research project “Study of the corrective effect of mesenchymal stem cells on the regeneration of damaged tissues…” (No. 0124U000058).
2023–2025: Scientific supervisor of the research project “Morphological and metabolic aspects of carcinogenesis” (No. 0123U100070).
2021–2023: Investigator on the state-funded research project “Study of the regenerative potential of cell therapy agents in ARDS” (No. 0121U100159).
2020–2021: Investigator on RECOOP Grant #028 Fusion Grant “COVID-19 disease and comorbidities during pregnancy”.

Professional experience and key skills

Electron microscopy: study of the ultrastructural organization of cells by transmission electron microscopy.
Histological studies and immunohistochemistry: assessment of tissue organization and of proliferation and apoptosis markers.
Head of the Ternopil branch of the Scientific Society of Anatomists, Histologists and Topographic Anatomists of Ukraine (since 2019).
Supervised to completion: 1 Candidate of Medical Sciences and 8 PhD candidates.

Key publications

Dzyubanovsky IYa, Nebesna ZM, et al. Microscopic and ultrastructural characterisation of the diaphragmatic central tendon... Arch Balk Med Union. 2026.
Dovhaliuk AI, ... Nebesna ZM, et al. Acellular dermal matrix for chronic wound treatment: dry or wet? Ukr Biochem J. 2026.
Kramar S.B., ... Nebesna Z.M. Oxidative stress and thymus morphology in colon carcinogenesis... World of Medicine and Biology. 2025.
Nebesna Z. M., et al. Peculiarities of histological and immunohistochemical changes in the respiratory portion of the white rats' lungs... Reports of Morphology. 2025.
Kramar, S., Nebesna, Z., et al. Changes in Placentas of Pregnant Women Infected with COVID-19. Int J Mol Sci. 2025.
Kramar S. B., ... Nebesna Z. M. Effect of metal nanoparticles usage on oxidative stress indicators... The Ukrainian Biochemical Journal. 2024.
Vari SG, ... Nebesna Z, et al. Common mechanisms of placental dysfunction in preeclampsia, gestational diabetes, and COVID-19... Ukr Biochem J. 2023.
Soroka YV, ... Nebesna ZM. The study of bcl-2 c938a gene polymorphism is promising for assessing The risk of occurrence... EuroBiomed J. 2022.

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Education

2022: PhD (specialty 091 Biology), I. Horbachevsky TNMU.
2018: Master’s degree (Research Biologist), Uzhhorod National University.

Positions

2026 – present: Associate Professor, Department of Histology and Embryology, TNMU.
2025 – present: Lead Specialist (concurrent position), ITRL of the ILC, TNMU.
2024–2025: Junior Researcher, Central Research Laboratory of the ILC, TNMU.
2022–2025: Assistant, Department of Histology and Embryology, TNMU.
2018–2025: Senior Laboratory Technician, ITRL of the ILC, TNMU.

Project management experience and traineeships

2025–2026: Member of the Erasmus+ project OPEN4UA “Open Science for the Ukrainian Higher Education System”.
2024–2025: Investigator on the state-funded research project “Application of regenerative medicine technologies for the treatment of chronic wounds” (0124U001099).
2023–2025: Responsible investigator of the research project “Morphological and metabolic aspects of carcinogenesis” (0123U100070).
2022: Erasmus+ professional traineeship at the Center for Research in Molecular Medicine (University of Santiago de Compostela, Spain).

Key research skills

Electron microscopy: preparation of semi-thin and ultrathin sections and contrasting.
Molecular biology: immunoblotting (EUROLINE), Western blot, quantitative real-time PCR (RT-qPCR).
Digital histology: digital and morphometric analysis (ImageJ, ToupView, SEO ImageLab Bio).

Key publications

Dovhaliuk AI, ... Ohinska NV, et al. Acellular dermal matrix for chronic wound treatment: dry or wet? Ukr Biochem J. 2026.
Chebernina IO, Nebesna ZM, Ohinska NV, et al. Histological changes in the dentate gyrus of the hippocampus... Reports of Morphology. 2025.
Rymar AA, ... Ohinska NV, et al. Changes in redox homeostasis in lung tissue under conditions of dm-induced colon adenocarcinoma. The Odesa Medical Journal. 2024.
Kulbitska VV, Ohinska NV, et al. Ultrastructure of adrenal glands endocrinocytes after thermal skin injury... Reports of Morphology. 2024.
Redko O, ... Ohinska N, et al. Mesenchymal stem cell therapy modulates macrophage dynamics in ARDS-associated liver injury... Cell and Organ Transplantology. 2023.
González-Vila A, ... Ohinska N, et al. Astrocytic insulin receptor controls circadian behavior via dopamine signaling... Nat Commun. 2023.
Ohinska NV, Nebesna ZM, Getmanyuk IB. Micro- and submicroscopic changes of the cerebellar cortex 21days after modeling the burn. Reports of Morphology. 2020.

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Education

2016: PhD in Biology — I. Horbachevsky Ternopil National Medical University. Thesis defended on 19 June 2016.
2011: Master of Biology — Ivan Franko National University of Lviv.

Positions and professional experience

01/2019 – present: Associate Professor, Department of Histology and Embryology, TNMU.
11/2018 – present: Head of the Histology and Immunohistochemistry Laboratory, TNMU.
10.03.2024 – 23.06.2026: Postdoctoral researcher — CERAMIC team, I2MC, INSERM / University of Toulouse, France.
01.09.2022 – 28.02.2023: Postdoctoral researcher — CERAMIC team, UMR 1297 / University of Toulouse III – Paul Sabatier, France.
11/2017 – 12/2018: Senior Lecturer, Department of Histology and Embryology, Ternopil State Medical University.
08/2015 – 11/2017: Assistant, Department of Histology and Embryology, Ternopil State Medical University.
08/2011 – 08/2015: Laboratory Technician, Department of Histology and Embryology, Ternopil State Medical University.

Project management and grants

2025–2028: “Features of structural and metabolic changes in tissues and organs of experimental animals in pathological conditions of various origins” — Principal Investigator.
2025–2026: “INSPIRE Mouse Cohort: A Comprehensive Longitudinal Study on Aging and Geroscience” — researcher, Toulouse, France.
2024–2026: “Application of regenerative medicine technologies for the treatment of chronic wounds” — researcher.
2023–2025: “Morphological and metabolic aspects of carcinogenesis” — researcher.
2021–2024: “Study of the regenerative potential of cell therapy in acute respiratory distress syndrome” — researcher.
2020–2023: RECOOP Grant #028 FG “COVID-19 disease and comorbidities during pregnancy” — Principal Investigator, RECOOP / Cedars-Sinai Medical Center, USA.
2018–2020: “Immunogenicity of malignant growth: the influence of Bcl-2 gene expression on antitumor immunity and under the corrective influence of nanomaterials” — researcher.

Traineeships and academic activity

2025–2026: Manuscript reviewer for international academic journals published by Frontiers, Springer Nature and MDPI.
2022–2024: Laureate of the PAUSE Program — postdoctoral fellowship.
2022: ERASMUS+ Staff Mobility — University of Toulouse III – Paul Sabatier (France) and ERASMUS+ KA107 Teaching Staff Mobility — University of Santiago de Compostela (Spain).
2018: ERASMUS+ “Modern Laboratory Techniques & Methods” — University of Toulouse III – Paul Sabatier.
2016: Familiarization with the work of the CSD Health Care laboratory — Kyiv, Ukraine.
2012: Training in “Basic Principles of Immunohistochemical Studies” — State Pathology Center of Ukraine.

Key research skills

Histology, immunohistochemistry and imaging: preparation of paraffin and cryosections, IHC and IF on sections, confocal and electron microscopy, morphometric analysis.
Cell cultures: H9c2, primary cardiac fibroblasts. Experience with models of myocardial infarction, ischemia-reperfusion, TAC and colorectal cancer.
Molecular biology: RNA and protein isolation, Western blot, RT-qPCR, ELISA, genotyping.
Digital pathology: quantitative analysis in QuPath and Fiji/ImageJ; data processing in GraphPad Prism.

Key publications

Kramar, S., Nebesna, Z., Yakymchuk, Y., et al. (2025). Changes in Placentas of Pregnant Women Infected with COVID-19. International journal of molecular sciences, 26(17), 8596.
Cinato, M., Kang, R., Kramar, S., et al. (2025). Transcriptome fingerprinting of aberrant fibroblast activation unlocks effective therapeutics to tackle cardiac fibrosis. Science advances, 11(33), eadx0968.
Savchenko, L., Kramar, S., et al. (2024). Galanin Coordinates Macrophage-Associated Fibro-Inflammatory Response and Mitochondrial Integrity in Myocardial Infarction Reperfusion Injury. Int. journal of molecular sciences, 25(11), 6211.
Kramar, S. B., Soroka, Y. V., et al. (2024). Structural changes in the organs of the lymphoid system in terms of induced carcinogenesis. Reports of Morphology, 30(3), 5–14.
Palii, I., Dovgalyuk, A., Kramar, S., & Korda, M. (2024). Changes in the macrophage polarization in the kidneys of rats with acute respiratory distress syndrome... Cell and Organ Transplantology, 12(2), 102–109.
Boal, F., Cinato, M., Timotin, A., ... Kramar, S., et al. (2022). Galanin regulates myocardial mitochondrial ROS homeostasis and hypertrophic remodeling through GalR2. Frontiers in Pharmacology, 13, 869179.
Martinelli, I., Timotin, A., ... Kramar, S., et al. (2021). Galanin promotes autophagy and alleviates apoptosis in the hypertrophied heart through FoxO1 pathway. Redox Biology, 40, 101866.
Loi, H., Kramar, S., et al. (2021). Metformin attenuates postinfarction myocardial fibrosis and inflammation in mice. International Journal of Molecular Sciences, 22(17), 9393.
Zykova, N., Kramar, S., et al. (2021). Ultrastructural changes of capillaries of the rat exocrine pancreas at the late burn injury... Cell and Organ Transplantology, 9(2), 116–124.
Rytsyk, O., ... Kramar, S., & Lisnychuk, N. (2020). Experimental evaluation of the effectiveness of resveratrol as an antioxidant in colon cancer prevention. Natural Product Communications, 15(6), 1–10.

The ILC team

Oleksandr Kamyshnyi

Liliya Logoyda

Mariana Horyn

Ihor Berdey

Nadiya Zarivna

Liubomyr Kryskiv

Tetiana Kucher

Olha Poliak

Olena Pokryshko

Taras Pyatkovskyy

Nataliya Kravets

Lidiya Romanyuk

Iryna Volch

Halyna Mykhailyshyn

Iryna Andriichuk

Mykhailo Buchynskyi

Liubov Kalinichuk

Alina Dovgalyuk

Pulkit Mittal

Halyna Voloshyn

Mariia Dziuba

Larysa Melnyk

Olha Marchuk

Zoia Nebesna

Nataliya Ohinska

Yuliana Shtohryn

Solomiia Kramar

Oksana Kindzerevych

Valentyna Plotnykova