Equipment available for booking

Available studies and methods

Identification and quantification of active pharmaceutical ingredients (APIs) in substances and finished dosage forms. Determination of related impurities and degradation products and assessment of the purity of medicinal products. Stability-indicating studies and analysis of samples after stress testing. Analysis of combination medicinal products with simultaneous determination of several active substances. Research in pharmaceutical chemistry, pharmaceutical analysis and standardization of medicinal products.

Technical specifications

• Injection volume range: 1–100 µl (typically 2–20 µl).
• Sample volume: 0.5–2 ml in standard HPLC vials (2 ml).
• Column oven temperature: from ambient to 80 °C.
• Maximum system operating pressure: up to 30 MPa (300 bar).
• Mobile phase flow rate: 0.1–2.0 ml/min (depending on the method).
• Detection: UV/DAD, wavelength range 190–800 nm.
• Column types: analytical columns 100–250 mm × 4.6 mm (or other compatible formats).
• Elution modes: isocratic and gradient.

Sample and consumable requirements

Test samples must be prepared as clear solutions, filtered through 0.22 or 0.45 µm membrane filters and placed in standard capped HPLC vials (2 ml). The researcher must provide information on the sample composition, analyte concentration, solvent, expected components and the purpose of the analysis. Typical matrices: pharmacopoeial reference standards (substances) and dosage forms.

Data export format

Electronic reports in PDF, Excel (XLS/XLSX), CSV and text formats suitable for further statistical processing.

Responsible specialist

Mariana Horyn
[email protected] | +380976111685

Available studies and methods

Identification of active substances in medicinal products, identification of components of complex mixtures, quality control of herbal medicinal products and medicinal plant raw materials, assessment of the purity of medicinal products, and research in pharmaceutical chemistry, pharmaceutical analysis and standardization of medicinal products.

Technical specifications

• Manufacturer: Supelco® (Merck KGaA, Germany) — a benchtop system for TLC documentation and densitometric evaluation.
• TLC plate format: up to 20 × 20 cm.
• Light sources: three LED sources illuminating the plate from above (direct-light mode).
• Software: automatic track recognition, auto-rotation of images of misaligned plates, background-noise reduction filters, automatic detection of the start line and solvent front with manual adjustment; simultaneous processing of several plates, analysis in under 2 minutes.
• Analysis capability: TLC/HPTLC plates.
• Visualization modes: VIS, UV at 254 and 366 nm.

Sample and consumable requirements

Test samples and, where required, reference standards. Prepared TLC/HPTLC plates, appropriate solvents, mobile phases and derivatization reagents are required according to the method. Plates are loaded into the TLC Explorer after the chromatographic run is complete and the plate has dried.

Data export format

Digital images of TLC/HPTLC plates in VIS and UV 254 and 366 nm modes; Rf values; densitograms and quantitative parameters of chromatographic zones (intensity, area/integrated signal); electronic data suitable for export, documentation and further statistical processing.

Responsible specialist

Nadiya Zarivna
[email protected] | +38(097)9308960

Available studies and methods

Potentiometric titration of medicinal products and substances: acid–base titration in aqueous and non-aqueous media (SPhU/Ph. Eur. 2.2.20), precipitation titration and redox titration. Automatic plotting of titration curves with determination of equivalence points. Calculation of the active substance content as a percentage. The methods comply with the requirements of the State Pharmacopoeia of Ukraine, Ph. Eur. and USP.

Technical specifications

• Titration algorithms: dynamic (DET), monotonic (MET) and set end point (SET).
• Potential measurement range: ±1200 mV.
• Measurement modes: pH / mV / °C.
• Burette drive resolution: 1/20,000 of the nominal volume.
• Control software: tiamo OMNIS (compliant with 21 CFR Part 11 / EU Annex 11).

Sample and consumable requirements

Samples: liquids, or solids dissolved in an appropriate solvent (0.1–2.0 g). For aqueous media, a solution in distilled or CO₂-free water; for non-aqueous media, in acetic acid or acetonitrile.

Consumables (supplied by the researcher): titrants (NaOH, HCl, HClO₄, AgNO₃, KMnO₄ and others), solvents and primary standards for titrant standardization. Reference electrode electrolyte (3M KCl or 1M KNO₃) is topped up as required.

Data export format

Results are stored in a secure tiamo OMNIS database with a full audit trail. Export to PDF (report with titration curve and calculations) and CSV for statistical processing (Excel, GraphPad Prism, Statistica).

Operating instructions

Advance booking is mandatory. Before starting work, check the condition of the electrodes and the electrolyte level and rinse with distilled water. Standardize the titrant before each series of analyses. After work, rinse and clean the cell and store the electrodes in the appropriate solution.

Responsible specialist

Liubomyr Kryskiv
[email protected] | 0682252725

Available studies and methods

Absorbance measurement at one or several selected wavelengths; wavelength scanning with the option of further spectral processing.

Technical specifications

• Optical design: double-beam.
• Equipment: multi-position (6-position) cuvette holder.
• Spectral range: 190–1100 nm.
• Scanning speed: from 10 nm/min to 3000 nm/min.

Sample and consumable requirements

Compatible with cuvettes of 1 cm optical path length. Reagents, reference standards and the necessary laboratory glassware are supplied by the researcher.

Data export format

The Shimadzu UV-1800 runs UV-Probe 2 software, which allows numerical data to be saved in .csv and .txt formats and spectra to be saved as λ/A tables for further processing.

Operating instructions

Advance booking is mandatory before starting work.

Responsible specialist

Tetiana Kucher
[email protected] | +380685159719

Available studies and methods

Measurement of pH, oxidation–reduction potential (ORP, mV) and temperature in aqueous solutions.

Technical specifications

• Measurement ranges: pH 0.00–14.00 (accuracy ±0.01 pH); potential from −2000 to +2000 mV; temperature 0–100 °C.

Sample and consumable requirements

Liquid or aqueous solutions, homogeneous and free from significant particulate matter, with a volume of at least 20 ml (20–25 °C). Required: a combined glass pH electrode, buffer solutions and KCl solution.

Data export format

The display shows pH, temperature and potential. Data are collected and transferred manually.

Responsible specialist

Olha Poliak
[email protected] | +380674565195

Available studies and methods

Routine pharmacopoeial analyses (residual water in APIs, moisture content of excipients) and research in the pharmaceutical, food and chemical industries.

Technical specifications

• Water determination range from 1 µg to 100%, automatic potentiometric titration, dosing resolution of 1/20,000 of the burette volume, compliance with GLP/GMP.

Sample and consumable requirements

Liquid or solid homogeneous samples protected from atmospheric moisture. Minimum quantity: from 10 mg (solids) or from 0.1 ml (liquids). Required: Karl Fischer reagents and anhydrous methanol.

Data export format

Results (water mass, %, ppm). Export via tiamo™ to LIMS, SQL databases, ERP systems and ELN.

Responsible specialist

Olha Poliak
[email protected] | +380674565195

Available studies and methods

The Electrolab EH-01P electronic hardness tester is designed for testing the mechanical properties of solid dosage forms in accordance with the requirements of the State Pharmacopoeia of Ukraine.

Technical specifications

• Manufacturer: Electrolab (India) Pvt. Ltd.; portable design, compliant with USP and the State Pharmacopoeia of Ukraine.
• Measured parameter: breaking force (crushing strength), measured by a load cell.
• Range: up to 500 N; minimum load 0.1 N.
• Accuracy: ±0.5 % of full scale.
• Tablet size: from 2 to 28 mm (length or diameter).
• Units of measurement: N, kgf, lbf.
• Result handling: display and print-out of 10 values with statistics; programmable upper (T1) and lower (T2) tolerance limits.
• Interface and power: RS-232 port for a printer; rechargeable Ni-Hi 8.4 V battery.

Data export format

The display shows the result in N (newtons).

Responsible specialist

Ihor Berdey
[email protected] | +38-067-793-96-46

Available studies and methods

Designed for the gentle drying of thermolabile APIs prone to oxidation or decomposition, plant extracts and excipients.

Technical specifications

• Manufacturer: SPE Ukrorgsintez LLC (Ukraine).
• Operating temperature range: from (ambient temperature +5) to +200 °C.
• Vacuum level: from 0.002 bar.
• Chamber volume: 50 l; internal dimensions (W × D × H) 350 × 450 × 350 mm.
• Materials: AISI 304 stainless steel chamber, aluminum shelves (3 as standard).
• Control: microprocessor temperature and time controller; up to 32 segments in a single drying program.
• Time to reach 200 °C: about 150 min (unloaded chamber).
• Power supply: 220 V ± 10 %, 50 Hz; rated power 1600 W.

Data export format

The display shows time, temperature and vacuum level.

Responsible specialist

Ihor Berdey
[email protected] | +38-067-793-96-46

Available studies and methods

The Electrolab EF-2 twin-drum tester is designed for testing solid dosage forms (mainly uncoated tablets) for mechanical strength, friability and resistance to chipping during transport, filling and packaging.

Technical specifications

The Electrolab EF-2 twin-drum friability tester supports standard Roche drums and abrasion drums at 25 rpm (adjustable within 20–50 rpm with an accuracy of ±1 rpm), allowing tests to be run either in precise counter mode (from 1 to 99,999 revolutions) or in timer mode (up to 99 h 59 min). The instrument is fitted with a mechanism for tilting the working axis by 10° for testing samples of specific shapes in accordance with USP/SPhU requirements, and with a system for automatic tablet unloading without removing the drums.

Data export format

The display shows the elapsed time.

A text test report (ASCII/text) can be sent to a connected printer via RS-232 or Centronics ports.

Transfer to a PC: a stream of numerical data via the RS-232 interface into laboratory software.

Responsible specialist

Ihor Berdey
[email protected] | +38-067-793-96-46

Available studies and methods

The instrument is designed to study the rate and completeness of API release from solid dosage forms in vitro. It meets the requirements of the State Pharmacopoeia of Ukraine, Ph. Eur. and USP. It is used for assessing bioavailability, developing new formulations and monitoring product stability (USP, EP, JP).

Technical specifications

• Number of stations: 6 vessels (1000 ml each).
• Apparatus types: Apparatus 1 (basket) and Apparatus 2 (paddle) according to SPhU / USP / Ph. Eur.
• Rotation speed: 20–250 rpm (±1 rpm).
• Temperature control: maintained up to 45 °C (accuracy in the vessel ±0.5 °C).

Data export format

A text test report (ASCII/text) can be sent to a connected printer via RS-232 or Centronics ports.

Transfer to a PC: a stream of numerical data via the RS-232 interface into laboratory software.

Responsible specialist

Ihor Berdey
[email protected] | +38-067-793-96-46

Available studies and methods

The disintegration test determines whether tablets or capsules disintegrate within a specified time when placed in a liquid medium under the prescribed experimental conditions.

Technical specifications

• The instrument is equipped with two working stations.
• Rate of vertical movement: 30 cycles/min.
• Stroke height: 55 mm.
• Each working station is fitted with 6 vessels meeting USP requirements.
• Automatic stopping of the working station in the upper position.
• Silent station drive.
• Transparent, illuminated water bath for better visibility.
• Built-in water thermostat maintaining temperature to within ±0.2 °C. Temperature is monitored by an immersion probe and shown on the display.
• Timer for setting the test duration, with the duration shown on the display.
• Digital membrane keypad.

Data export format

The display shows the disintegration time.

Responsible specialist

Ihor Berdey
[email protected] | +38-067-793-96-46

Available studies and methods

Determination of the refractive index of liquids in pharmaceutical, food and chemical analysis, control of solution concentration, identification of substances and detection of signs of adulteration.

Technical specifications

• Measurement range: 1.300–1.700 (error up to ±0.0002–0.0005).

Sample and consumable requirements

Homogeneous liquid samples free from air bubbles (from 0.05 ml, at 20 ± 0.5 °C). Required: purified water, reference liquids, pipettes and lint-free wipes.

Data export format

Visual reading from the instrument’s optical scale. Results are entered into the logbook manually.

Responsible specialist

Olha Poliak
[email protected] | +380674565195

Available studies and methods

Determination of the specific rotation of substances, identification of optically active compounds, quality control of medicinal products and analysis of extemporaneous dosage forms.

Technical specifications

• Measurement range: from −180° to +180° (accuracy ±0.05°).

Sample and consumable requirements

Clear homogeneous solutions (2–20 ml depending on the tube, at 20 ± 0.5 °C). Required: polarimeter tubes (50–200 mm), quartz reference plates and standard sucrose solutions.

Data export format

Visual reading from the instrument scale. Data are entered into electronic systems manually.

Responsible specialist

Olha Poliak
[email protected] | +380674565195

Available studies and methods

Quantitative real-time PCR (qPCR), gene expression analysis and SNP genotyping.

Technical specifications

• 96-well thermal block, temperature gradient (30–100 °C), 6-channel optical system for multiplex analysis.

Sample and consumable requirements

Low-profile 96-well PCR plates (0.2 ml) or strip tubes with optical caps. Reagents (primers, probes, master mix) are supplied by the researcher.

Data export format

Export of raw amplification curves in .csv, .txt and .pcrd formats (files are easily imported into JASP or GraphPad Prism).

Responsible specialist

Olha Marchuk
[email protected]

Available studies and methods

Quantitative and qualitative real-time PCR and HRMA (high-resolution melting curve analysis).

Technical specifications

• Rotary thermal block format (provides high temperature uniformity), up to 6 fluorescence channels.

Sample and consumable requirements

Dedicated tubes for rotary thermal cyclers (0.1 ml or 0.2 ml). All reagents are supplied by the researcher.

Data export format

.csv and .txt formats, and the proprietary .rex format for the manufacturer’s own software.

Responsible specialist

Olha Marchuk
[email protected]

Available studies and methods

Automated syndromic testing for infectious diseases by multiplex real-time PCR. The system can simultaneously detect and differentiate dozens of pathogens (viruses, bacteria and fungi) from a single clinical sample. Respiratory, gastrointestinal and meningitis/encephalitis panels are available. It is suitable for molecular epidemiological surveillance.

Technical specifications

• Principle of operation: fully automated sample-to-result workflow — nucleic acid extraction, amplification and detection all take place in a single closed cartridge.
• Analysis time: results in approximately 1 hour.
• Format: single-use multiplex cartridges (detection of up to 48 targets in one test).
• Detection: real-time fluorescence detection.
• Control: built-in touch screen and direct integration with laboratory information systems (LIS).

Sample and consumable requirements

Original QIAstat-Dx test cartridges are required. Samples (nasopharyngeal swabs, aspirates, stool samples) are loaded directly into the cartridge without prior manual sample preparation, which reduces the risk of contamination.

Data export format

The system generates detailed clinical reports in PDF format with qualitative results (detected / not detected) for each pathogen. For research purposes, threshold cycle (Ct) values and amplification curves can be exported.

Responsible specialist

Olha Marchuk
[email protected]

Available studies and methods

The system is designed for the complete cycle of reading and preparing 96-well plates in enzyme immunoassays (ELISA). It is used for the quantitative and qualitative determination of biological markers: thyroid hormones, the reproductive panel, tumor markers, infectious disease markers, autoimmune antibodies and others.

Reader specifications (EIAQuant)

• Optical system: 8-channel reading system with a halogen lamp.
• Wavelength range: 400–800 nm (filters at 405, 450, 492 and 630 nm).
• Reading speed: approximately 5 seconds for a monochromatic read of the whole plate.
• Calculation methods: Absorbance, Cut-off, Multi-standard, Linear/Non-linear Regression.

Washer specifications (EIAWash)

• Wash head: 8-channel, compatible with U-, V- and flat-bottom plates.
• Dispensing: from 50 µl to 3000 µl per well, with a minimal residual volume (< 2 µl).
• Automation: configurable number of wash cycles, soaking time (up to 24 h) and shaking.

Sample and consumable requirements

Standardized ELISA test kits are used. The researcher supplies the plates/strips, reagents (conjugates, substrates, stop solutions) and wash buffers according to the chosen method.

Responsible specialist

Olha Marchuk
[email protected]

Available studies and methods

An open-type microplate photometer for colorimetric assays and enzyme immunoassays (ELISA) in research and clinical laboratories.

Technical specifications

• System type: open-type analyzer for 96-well microplates.
• Optics: wide wavelength range (typically 340–850 nm depending on the filters installed).
• Speed and accuracy: rapid plate reading with high linearity and reproducibility of optical density.
• Operating conditions: operating temperature range from +10 °C to +40 °C.

Sample and consumable requirements

Reagents, microplates and other consumables are supplied by the researcher in accordance with the protocol of the specific test kit.

Data export format

The analyzer reports results as numerical values (optical density). Data are shown on screen and can also be exported to a PC via dedicated software (SkanIt) or printed directly.

Responsible specialist

Olha Marchuk
[email protected]

Purpose and capabilities

An upright freezer for long-term storage of biological material, reagents and kit components for biochemical and enzyme immunoassay studies that require freezing.

What is stored in the unit

• Biological samples: aliquots of serum, plasma and tissue homogenates awaiting analysis.
• Calibrators and controls: aliquots of standards and control materials.
• Kit components: reagents that the manufacturer requires to be stored frozen.
• Enzymes and thermolabile reagents: long-term storage at sub-zero temperatures.
• Cold packs: cooling elements for transporting samples.

Technical specifications

• Type: free-standing upright freezer cabinet.
• Volume: 303 L gross, 262 L usable.
• Temperature range: approximately −14 to −22 °C.
• Cooling system: frost-free (No Frost).
• Freezing capacity: 24 kg/day.
• Cold retention without power: up to 12 h.
• Interior: 4 plastic drawers and 2 tempered glass shelves.
• Refrigerant: R600a.
• Dimensions (H × W × D): 185 × 60 × 66 cm.

Storage requirements and rules of use

Samples are stored in tightly closed cryotubes or containers labeled with the sample code, name and date. Material is aliquoted in advance to avoid repeated freeze–thaw cycles. Storing food in the unit is prohibited.

Important: the freezer does not reach ultra-low temperatures, so material that must be kept at −80 °C is not stored in it. The unit is not explosion-proof — storing volatile flammable solvents is prohibited.

Data export format

The unit does not generate research data. The output of its operation is a temperature monitoring log confirming that samples and reagents have been stored under appropriate conditions.

Operating instructions

The placement of materials is agreed with the responsible specialist. The temperature is checked and recorded in the log. The door should not be kept open for longer than is needed to remove a sample. During a power outage the freezer is kept closed. Any temperature deviation must be reported to the responsible specialist immediately.

Responsible specialist

Olha Marchuk
[email protected]

Available studies and methods

Full blood count.

Technical specifications

• Closed-type automatic hematology analyzer.
• Operating modes: CBC mode (complete blood count) and DIFF mode (CBC plus white blood cell differential).
• Throughput: about 50 samples per hour.
• Operating temperature: from +15 °C to +30 °C.

Sample and consumable requirements

Only reagents intended for this analyzer may be used. Reagents and consumables are supplied by the researcher.

Data export format

The analyzer reports results as numerical values (up to 37 hematology parameters in DIFF mode, per the manufacturer’s specification), cell distribution histograms and white blood cell differentiation matrices. All data are shown on the display. Data transfer: printout.

Operating instructions

Advance booking is mandatory. The system must be cleaned after use.

Responsible specialist

Halyna Voloshyn
[email protected] | 096 737 21 69

Available studies and methods

Biochemical assays.

Technical specifications

• Open-type analyzer.
• Capabilities: touch screen with a virtual alphanumeric keypad, 200 programmable tests.
• Memory: storage of 1000 results sorted by date.
• Quality control: three-level control for every test.
• Equipment: built-in 6-position incubation block and built-in flow cell pump.
• Operating temperature: from +15 °C to +30 °C.

Sample and consumable requirements

Reagents and plastic consumables are supplied by the researcher.

Data export format

The analyzer reports results as numerical values. Data transfer: printout.

Operating instructions

Advance booking is mandatory. The system must be cleaned after use.

Responsible specialist

Mariia Dziuba
[email protected] | 067 742 82 48

Available studies and methods

Coagulation profile.

Technical specifications

• Open reagent system.
• Test channels: 2.
• Reagent pre-warming positions: 2, at 37 °C.
• Sample volume: 50–200 µl.
• Reagent volume: 50–100 µl.
• Reaction mixture volume: 150–300 µl.
• Operating temperature: +10 °C to +30 °C.

Sample and consumable requirements

Reagents and plastic consumables are supplied by the researcher.

Data export format

The instrument reports results as numerical values. Data transfer: printout.

Operating instructions

Advance booking is mandatory.

Responsible specialist

Mariia Dziuba
[email protected] | 067 742 82 48

Available studies and methods

Enzyme immunoassays.

Technical specifications

• Open-type analyzer.
• 96-well plates.
• Operating temperature: from +10 °C to +40 °C.

Sample and consumable requirements

Reagents and plastic consumables are supplied by the researcher.

Data export format

The analyzer reports results as numerical values. Data transfer: printout.

Operating instructions

Advance booking is mandatory.

Responsible specialist

Larysa Melnyk
[email protected] | 097 720 36 86

Available studies and methods

An instrument for biochemical assays operating as an open system and based on the measurement of biochemical parameters. It supports kinetic calculation methods, including standard-based calculation, and end-point calculation. It operates in semi-automatic mode.

Technical specifications

• Country of manufacture: Germany.
• Measurement methods: end point, kinetics, two-point kinetics, differential mode, dual-wavelength methods.
• Interference filters: 340, 405, 505, 545, 580 and 630 nm (2 additional filters can be installed). Automatic and manual filter selection.
• Calculation methods: by standard, by factor, non-linear calibration.
• Reagent consumption: from 250 to 1000 µl per measurement.
• Display range: 0.5–3.5 absorbance units. Resolution: 0.0002 A/min.
• Measurements can be made in a fill cuvette, a flow cell or a standard test tube.
• The instrument is configured according to the selected method and chemical reagent. Quality control of reaction dynamics and recording of reaction range parameters.
• Internal memory holds 60 diagnostic test types. Supplied with a thermostat for twelve test methods.

Sample and consumable requirements

Appropriate test kits; blood serum, urine, bile.

Data export format

Automatic processing of assay results with output to the instrument display. Data are recorded in a digital laboratory log. A built-in or external printer can be connected to print the results.

Responsible specialist

Iryna Andriichuk
[email protected]

Available studies and methods

Measurement of optical density in biochemical and immunological (biochemical method) assays. A single-beam laboratory instrument for quantitative analysis and measurement of transmittance or optical density.

Technical specifications

• Manufacturer: DLAB Scientific Co., Ltd. (the same platform is also supplied under the Scilogex SCI-V1000 brand).
• Optical system: single-beam.
• Spectral bandwidth: 4 nm.
• Light source: tungsten lamp.
• Wavelength range: 325–1000 nm. Wavelength accuracy: ±2 nm.
• Photometric range: −0.3 to 3.0 A, 0–200% T.
• Stray light: ≤0.3% T below 360 nm.
• Stability: 0.002 A/h at 500 nm (after warm-up).
• Sample compartment: 4 cuvettes (10 mm optical path), 1 × 1 cm.
• Cuvettes: accepts cuvettes of 5–100 mm path length.
• Memory: stores 200 results (with automatic overwrite) and 200 standard curves in the instrument’s built-in memory.
• Display: LCD. Interfaces: USB port and parallel printer port.
• Power supply: 110/220 V, 50/60 Hz. Power consumption: 80 W.
• Dimensions: 490 × 360 × 210 mm. Weight: 12 kg.

Sample and consumable requirements

Clean samples of biological fluids. Consumables are reagents prepared under clean conditions in distilled water or physiological saline.

Data export format

Data are shown on the display (and converted using the formula specified by the method).

Operating instructions (SOP)

• Preparation: switch the instrument on and allow it to warm up for 15–20 minutes so that the light source (tungsten lamp) stabilizes.
• Wavelength setting: the wavelength is set automatically from the control panel or a connected PC.
• Working with cuvettes: before measurement, wipe the optical surfaces of the cuvettes with a soft lint-free cloth. Always insert the reference sample (blank) first to zero the instrument (Abs/T%).
• Care: protect the cuvette compartment from spilled liquids and aggressive reagents.

Responsible specialist

Liubov Kalinichuk
[email protected]

Available studies and methods

Infections: hepatitis A (anti-HAV), HBsAg, HBeAg, HBcAg, HBsAg confirmatory, anti-HBsAg, hepatitis C (anti-HCV), chlamydia (antigens, IgG, IgA), toxoplasmosis (IgG, IgM), giardiasis, adenovirus (IgG, IgM), candidiasis, aspergillosis, Lyme disease, cytomegalovirus (IgG, IgM), Epstein–Barr virus (IgG, IgM), HIV 1,2 (antibodies), herpes simplex virus (IgG, IgM), varicella zoster virus (IgG, IgM), measles virus (IgG, IgM), influenza virus A and B (IgA, IgG, IgM), parainfluenza virus 1, 2, 3 (IgA, IgG, IgM), mumps virus (IgA, IgG, IgM), rubella virus (IgG, IgM), campylobacteriosis (IgG, IgM), poliomyelitis, diphtheria (IgG), echinococcosis (IgG), syphilis (IgG, IgM), yersiniosis, tetanus.

Tumor markers: alpha-fetoprotein, carcinoembryonic antigen, prostate-specific antigen, CA-125, CA-15-3, CA-19-9, CA-242, ferritin, hCG, NSE, tissue polypeptide antigen, beta2-microglobulin (bladder cancer).

Thyroid gland: triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), thyroglobulin, anti-thyroglobulin antibodies, anti-thyroid peroxidase antibodies, antibodies to thyrocyte microsomal antigens.

Reproductive function: prolactin, luteinizing hormone (LH), follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG), anti-sperm antibodies.

Endocrinology: cortisol, testosterone, androstenedione, progesterone, adrenaline, melatonin, serotonin, growth hormone, estradiol, estriol, ACTH, calcitonin.

Allergy: immunoglobulin E, antibodies to allergens, histamine.

Pregnancy: hCG in urine and serum.

Autoimmune and systemic diseases: rheumatoid factor, C-reactive protein, ASLO, antibodies to DNA and RNA (dsDNA, histones, SS-A, SS-B, RNP, Scl-70, Sm, Jo-1).

Technical specifications

• Semi-automatic microplate photometer (reader): the operator loads the plate and adds the reagents, while the instrument performs the reading and the calculations.
• Bichromatic optical system with 4 optical filters.
• Standard 96-well plates and individual strips.
• 8-channel fiber-optic system that reads a whole plate in 5 seconds.
• Large LCD display, software based on Windows CE.
• Built-in modem support for remote servicing and software updates.
• Operated via touch screen or an external mouse.

Sample and consumable requirements

Appropriate test kits; blood serum.

Data export format

Data are shown on the display.

Operating instructions (SOP)

• Power-on and self-test: connect the instrument to the AC mains (110–220 V). Switch on the power — the instrument runs an automatic self-test of the optical and internal systems. Lamp warm-up takes about 1 minute.
• Control: use the touch screen or a connected mouse with the built-in Windows-style software.
• Test programming: enter the assay method, select the wavelength (bichromatic photometry is available) and configure blanks and positive/negative controls. The memory holds up to 100 assay methods, 1,000 patient records and 10,000 results.
• Measurement: place the 96-well plate or individual strips in the plate holder. Start the scan from the menu. The 8-channel optical system reads the whole plate in just 5 seconds.
• Data processing: the instrument performs calculations using various mathematical models (absorbance, cut-off, linear regression, multi-point curve fitting and others).
• Reporting: review the report on the large LCD display and send it to an external printer.
• Safety and maintenance: keep the instrument in a dry room protected from excessive dust. Avoid using flammable liquids near the photometer. Clean the surfaces regularly and follow standard laboratory safety rules when working with biological material.

Responsible specialist

Iryna Andriichuk
[email protected]

Available studies and methods

Laboratory measurement of pH in aqueous solutions.

Technical specifications

• The instrument performs laboratory measurements of pH in aqueous solutions and of ORP.
• Manufacturer: Shanghai San-Xin Instrumentation; the same instrument is also supplied under the Apera Instruments MP511 brand.
• pH measurement range: −2.00 to 19.99 pH with a resolution of 0.01 pH — suitable for both concentrated acids and caustic alkalis.
• Temperature compensation: automatic (ATC) or, at the operator’s choice, manual.
• GLP compliance: automatic calibration against standard buffer solutions, data storage (up to 600 results), a measurement timer, an RS-232 output and self-diagnostics.
• Electrode: a combined plastic three-parameter electrode — pH, ORP and temperature — allowing comprehensive quality control of natural, tap and process water.
• Measurement modes: single (with stable-reading capture); continuous; timed.
• Operating conditions: ambient temperature from +5 to +35 °C.
• Supplied with: a flexible electrode stand.

Sample and consumable requirements

Consumables are reagents prepared under clean conditions in distilled water or physiological saline.

Data export format

Results are shown on the display.

Responsible specialist

Liubov Kalinichuk
[email protected]

Available studies and methods

Measurement of transmittance and optical density of solid and liquid samples in the visible and ultraviolet regions of the spectrum. Used for optical density measurement in biochemical and immunological (biochemical method) assays.

Technical specifications

• Functionality: LCD screen (128 × 64 pixels); the instrument displays and stores 200 data groups (5 groups per screen), as well as calibration and kinetic curves. Data are retained after the power is switched off.
• The wavelength is set automatically; the lamps are controlled independently.
• Computer control via the USB port (optional software required).
• 5 measurement modes: quantitative, kinetic, wavelength scanning and DNA/protein testing.
• Replacing a lamp does not affect the alignment of the optical system.
• Large cuvette compartment for 5–100 mm cuvettes (with additional holders).
• Spectral range: 190–1100 nm. Spectral bandwidth: 2 nm.
• Optical design: single-beam, 1200 lines/mm grating.
• Light sources: halogen and deuterium lamps.
• Wavelength setting accuracy: ±0.5 nm. Wavelength reproducibility: 0.3 nm.
• Photometric reproducibility: 0.2 %T. Photometric accuracy: ±0.3 %T.
• Stray light: 0.05 %T at 220 and 340 nm.
• Photometric range: −0.3 to 3.0 A; 0 to 200 %T.
• Stability: ±0.002 A/h at 500 nm.
• Cuvette holder: 4-position for 10 mm cuvettes.
• Digital output: USB port and parallel printer port.
• Power supply: 220 V/50 Hz or 110 V/60 Hz. Power consumption: 80 W.
• Dimensions: 470 × 370 × 180 mm. Weight: 14 kg.
• Supplied with: spectrophotometer, power supply unit, cuvettes (a set of 4 glass and a set of 2 quartz cuvettes) and the instrument manual.

Sample and consumable requirements

Clean samples of biological fluids. Consumables are reagents prepared under clean conditions in distilled water or physiological saline.

Data export format

Results are shown on the display (and converted using the formula specified by the method).

Operating instructions (SOP)

• Preparation: switch the instrument on and allow it to warm up (normally 15–20 minutes) so that the lamps stabilize (UV models are fitted with tungsten and deuterium lamps).
• Setup: use the LCD screen and control panel to select the measurement mode (transmittance, absorbance, concentration).
• Data storage: the instrument can store up to 200 data groups and calibration curves in memory.
• Maintenance: keep the cuvette compartment clean and avoid spilling aggressive liquids onto the surfaces and optical components.

Responsible specialist

Liubov Kalinichuk
[email protected]

Available studies and methods

Preparation of semi-thin (0.5–1 µm) and ultrathin (0.05–0.2 µm) sections of biological samples for subsequent examination by light and transmission electron microscopy.

Technical specifications

• Control of the dimensions of the block containing the biological material and of the density of the embedding medium.
• Use of glass or diamond knives for ultramicrotomy.
• Adjustment of cutting speed and specimen feed.
• Precise setting of the thickness of semi-thin and ultrathin sections.

Sample and consumable requirements

Samples must be pre-fixed, dehydrated and embedded in polymerizing (epoxy) resins to produce a hard composite block. The dimensions and shape of the block must be compatible with the ultramicrotome specimen holder.

Consumables (supplied by the researcher): glass or diamond knives, copper grids, forceps, filter paper, reagents for contrasting ultrathin sections (uranyl acetate and lead citrate) and ancillary materials.

Data export format

The instrument does not generate digital results. Its output consists of physically prepared sections, which are then examined under a microscope.

Operating instructions

Advance booking and prior instruction are mandatory. After the sectioning run is complete, the block must be cleaned and the workplace tidied in accordance with the standard operating procedure.

Responsible specialist

Zoia Nebesna
[email protected] | 0979791936

Available studies and methods

Transmission electron microscopy of biological specimens, ultrastructural analysis of cells and tissues, and study of subcellular structures and organelles. Visualization of biological nanostructures and extracellular vesicles (exosomes) by negative staining. Examination of ultrathin sections, acquisition of electron diffraction patterns and morphometric image analysis.

Technical specifications

• Manufacturer: SELMI JSC (Sumy, Ukraine).
• Cathode type: tungsten thermionic cathode.
• Accelerating voltage: range 25–125 kV.
• Electron-optical magnification: from 50× to 1,300,000×.
• Resolution: up to 0.14 nm lattice resolution and 0.35 nm point resolution.
• Digital recording of images and diffraction patterns.

Sample and consumable requirements

Ultrathin sections of biological samples mounted on copper electron microscopy grids with a support film are used. Sections must be uniform (free from folds and tears) and the grids must be clean. Before transmission microscopy, sections must be contrasted with heavy metal salts (uranyl acetate and lead citrate).

Data export format

Digital electron microscopy images are saved in the standard graphics formats TIFF, JPEG and PNG. The data are suitable for digital processing and for morphometric and statistical analysis in ImageJ and similar software.

Operating instructions

The instrument may be used only after prior arrangement and booking. The researcher must supply samples prepared according to electron microscopy protocols.

Responsible specialist

Zoia Nebesna
[email protected] | 0979791936

Purpose and capabilities

A two-compartment refrigerator-freezer for storing thermolabile reagents and biological material used in sample preparation for electron microscopy.

What is stored in the unit

• Fixative solutions: reagents for fixing biological material that require cold storage.
• Buffer systems: buffer and washing solutions for sample processing.
• Embedding reagents: components of embedding media, stored separately until the moment of mixing.
• Contrasting solutions: reagents for contrasting sections, in light-protected containers.
• Biological material: fixed tissue samples at intermediate stages of processing.
• Freezer compartment: long-term storage of reagent aliquots and frozen samples.

Technical specifications

• Type: free-standing two-compartment refrigerator with a bottom freezer.
• Refrigerator compartment: operating range +2…+8 °C.
• Freezer compartment: operating range down to −18 °C.
• Control: electronic unit with separate temperature regulation for each compartment.
• Cooling system: frost-free (No Frost) — more stable temperature and no need for defrosting.

Storage requirements and rules of use

All containers must be tightly closed and labeled with the name of the reagent, its concentration and the date of preparation. Reagents and biological material are kept on separate shelves to avoid cross-contamination. Storing food in the unit is prohibited.

Important: this is a domestic refrigerator without explosion-proof construction. Storing volatile flammable organic solvents in it (propylene oxide, acetone, ethanol in open containers) is prohibited — separate equipment is provided for these. Osmium tetroxide is stored exclusively in sealed secondary containers.

Data export format

The unit does not generate research data. The output of its operation is a temperature monitoring log kept to confirm that reagents have been stored under appropriate conditions.

Operating instructions

The placement of materials is agreed with the responsible specialist. Compartment temperatures are checked and recorded in the log. The door should not be kept open for longer than is needed to remove a sample. Any deviation of the temperature from the operating range must be reported to the responsible specialist immediately.

Responsible specialist

Zoia Nebesna
[email protected] | 0979791936

Available studies and methods

Gravimetric measurements during sample preparation for electron microscopy.

Main applications

• Preparation of solutions: weighing portions of dry reagents to prepare solutions of a defined concentration.
• Dosing of multi-component mixtures: measuring out components in precise mass ratios.
• Fixative and buffer solutions: weighing salts and reagents for fixing and washing samples.
• Contrasting reagents: preparation of solutions for contrasting sections.
• Sample mass control: weighing portions of biological material at the preparation stage.

Technical specifications

• Manufacturer: AXIS (Poland), laboratory balances for analytical and general laboratory tasks.
• Calibration: adjustment against an external or internal reference mass.
• Operating modes: taring, weighing in different units, counting of identical items and determination of percentage content.
• Design: draught shield to protect against air movement, adjustable feet and a spirit level for leveling.
• Data transfer: interface for connecting a printer or computer (depending on the model).

Operating and consumable requirements

The balance is installed on a stable surface free from vibration and draughts and away from direct sunlight. Before a series of measurements, the instrument is allowed to warm up and is adjusted if necessary. Weighing is carried out in clean vessels or weighing boats; aggressive and volatile substances are weighed only in closed containers.

Consumables (supplied by the researcher): weighing boats or vessels, spatulas, gloves and wipes for cleaning the pan.

Data export format

The result is shown on the display and entered in the working log. Where an interface is available, values can be sent to a printer or transferred to a computer for inclusion in the solution preparation record.

Operating instructions

Use is possible after booking and instruction. After each weighing the pan is cleaned and reagent residues are disposed of in accordance with the rules for handling chemical waste. Moving the balance without re-leveling and re-adjustment is not permitted.

Responsible specialist

Zoia Nebesna
[email protected] | 0979791936

Available studies and methods

Gravimetric measurements in the quality control of medicines and pharmaceutical substances.

Main applications

• Analytical portions: weighing portions of substances and dosage forms for assays (spectrophotometry, HPLC, titrimetry).
• Standard solutions: preparation of reference standard solutions and volumetric solutions.
• Uniformity of mass: determination of the average mass and uniformity of mass of tablets and capsules.
• Loss on drying: weighing samples before and after drying.
• Reagents and buffers: preparation of solutions for pharmacopoeial methods.

Technical specifications

• Manufacturer: AXIS (Poland), laboratory balances for analytical and general laboratory tasks.
• Calibration: adjustment against an external or internal reference mass.
• Operating modes: taring, weighing in different units, counting of identical items and determination of percentage content.
• Design: draught shield to protect against air movement, adjustable feet and a spirit level for leveling.
• Data transfer: interface for connecting a printer or computer (depending on the model).

Operating and consumable requirements

The balance is installed on a stable surface free from vibration and draughts and away from direct sunlight. Before a series of measurements, the instrument is allowed to warm up and is adjusted if necessary. Weighing is carried out in clean vessels or weighing boats; hygroscopic, aggressive and volatile substances are weighed only in closed containers.

Consumables (supplied by the researcher): weighing boats or weighing bottles, spatulas, gloves and wipes for cleaning the pan.

Data export format

The result is shown on the display and entered in the working log. Where an interface is available, values can be sent to a printer or transferred to a computer for inclusion in the test record.

Operating instructions

Use is possible after booking and instruction. After each weighing the pan is cleaned and residues are disposed of in accordance with the rules for handling chemical waste. Moving the balance without re-leveling and re-adjustment is not permitted.

Responsible specialist

Olha Poliak
[email protected] | +380674565195

Available studies and methods

Establishing and maintaining a set temperature in the working chamber over long periods during sample preparation for electron microscopy.

Main applications

• Sample embedding: stepwise holding of embedding blocks at increasing temperatures until they reach a hardness suitable for ultramicrotomy.
• Sample infiltration: accelerating the penetration of the embedding medium into the tissue at elevated temperature.
• Thermostatic control of solutions: maintaining the working temperature of reagents and buffers before use.
• Incubation: holding samples at a constant temperature during individual stages of histological and immunocytochemical processing.
• Drying: bringing slides, glassware and ancillary materials to a dry state.

Technical specifications

• Manufacturer: MIZ-MA LLC (MICROmed brand, Ukraine); certified to ISO 13485:2016.
• Type: dry-air incubator with forced air circulation in the chamber.
• Usable chamber volume: 20 dm³.
• Temperature range: from (ambient temperature +5) to +70 °C.
• Temperature setting increment: 0.1 °C.
• Accuracy: maximum deviation from the set temperature 0.4 °C; stability at the reference point 0.1 °C.
• Indication: continuous digital display of the current temperature.
• Chamber material: mirror-finish stainless steel; additional transparent inner door.
• Equipment: removable perforated shelves and thermally insulated walls.

Sample and consumable requirements

Pre-labeled embedding molds (capsules or flat molds) containing biological material, glassware or ancillary materials are placed in the chamber. They are arranged so as not to obstruct air circulation and without overloading the shelves. When working with volatile reagents the room must be ventilated.

Consumables (supplied by the researcher): embedding capsules or silicone molds, labels, embedding reagents and gloves.

Important: heating volatile flammable solvents or hermetically sealed containers of liquid in the incubator is prohibited.

Data export format

The instrument does not generate digital results. Its output consists of processed samples ready for the next stage of the study, together with a record of the regime and holding time in the sample preparation protocol.

Operating instructions

Before loading, the incubator is brought up to the working regime and the stability of the readings is confirmed. The set temperature and the start time of the holding period are recorded in the log. Opening the chamber during a run without good reason is not recommended, as this disturbs the temperature regime. After work is finished the chamber is cleaned of reagent residues.

Responsible specialist

Zoia Nebesna
[email protected] | 0979791936

Available studies and methods

Establishing and maintaining a set temperature in the working chamber over long periods during histological and immunohistochemical processing of samples.

Main applications

• Drying sections: fixing paraffin sections onto slides after microtomy, before dewaxing and staining.
• Working with paraffin: melting histological paraffin and keeping it liquid for infiltration and embedding of samples.
• Slide incubation: holding slides in humid chambers with primary and secondary antibodies at 37 °C during immunohistochemical reactions.
• Histochemical staining: methods that require solutions at elevated temperature.
• Thermostatic control of reagents: bringing buffers and working solutions to the set temperature before use.

Technical specifications

• Manufacturer: MIZ-MA LLC (MICROmed brand, Ukraine); certified to ISO 13485:2016.
• Type: dry-air incubator with forced air circulation in the chamber.
• Usable chamber volume: 20 dm³.
• Temperature range: from (ambient temperature +5) to +70 °C.
• Temperature setting increment: 0.1 °C.
• Accuracy: maximum deviation from the set temperature 0.4 °C; stability at the reference point 0.1 °C.
• Indication: continuous digital display of the current temperature.
• Chamber material: mirror-finish stainless steel; additional transparent inner door.
• Equipment: removable perforated shelves and thermally insulated walls.

Sample and consumable requirements

Slides with sections are placed in racks or on trays; humid chambers are kept level. Materials are arranged so as not to obstruct air circulation and without overloading the shelves.

Consumables (supplied by the researcher): slides (including adhesive slides), racks, humid chambers, paraffin and gloves.

Important: heating volatile flammable solvents (xylene, ethanol) or hermetically sealed containers of liquid in the incubator is prohibited.

Data export format

The instrument does not generate digital results. Its output consists of processed slides ready for the next stage of the study, together with a record of the regime and holding time in the protocol.

Operating instructions

Use is possible after booking and instruction. Before loading, the incubator is brought up to the working regime and the stability of the readings is confirmed. The set temperature and the start time of the holding period are recorded in the log. Opening the chamber during a run without good reason is not recommended. After work is finished the chamber is cleaned of paraffin and reagent residues.

Responsible specialist

Solomiia Kramar
[email protected] | +380961021042

Available studies and methods

Preparation of serial and single thin sections from paraffin blocks for light microscopy; routine histological staining (H&E, special histochemical techniques); immunohistochemical studies; morphometric and digital morphological analysis following subsequent scanning or photodocumentation.

Technical specifications

Section thickness range: 0–60 µm; increments: 0–2 µm in 0.5 µm steps; 2–10 µm in 1 µm steps; 10–20 µm in 2 µm steps; 20–60 µm in 5 µm steps. Trimming: 10 or 50 µm. Specimen retraction approximately 220 µm (can be switched off). Maximum specimen size 40 × 50 × 30 mm or a standard cassette. Vertical stroke 59 mm; horizontal feed 28 mm; specimen holder orientation ±8° horizontally and vertically. Compatible with low- and high-profile disposable blades.

Sample and consumable requirements

Material: tissues fixed and embedded in paraffin, in standard histology cassettes or paraffin blocks; the block must be correctly oriented and pre-cooled to the working temperature. Where required, the researcher supplies disposable microtome blades, slides (adhesive/charged for IHC) and labeling.

Data export format

Digital export is not provided. The output consists of physical paraffin sections on slides, or section ribbons, for subsequent staining, microscopy and/or digital scanning.

Operating instructions (SOP)

Before work, lock the handwheel, correctly mount the cassette/block and the blade and set the section thickness; when changing the specimen or the blade, use the handwheel lock and the blade holder guard. After work, remove paraffin waste and clean the working area.

Responsible specialist

Oksana Kindzerevych
+380676884949

Available studies and methods

Preparation of frozen tissue sections for rapid morphological analysis; cryohistology; histochemical and enzyme histochemical techniques; immunofluorescence and immunohistochemical studies on frozen sections; morphometry and digital analysis following microscopy or scanning.

Technical specifications

Minimum cryochamber temperature: −35 ± 2 °C; freezing shelf: −45 ± 5 °C; Peltier module on the shelf: down to −55 ± 5 °C; Peltier module on the specimen clamp: down to −50 ± 5 °C (Peltier duty cycle 15 min). Maximum specimen size 35 × 35 mm. Vertical stroke 48 ± 1 mm; horizontal feed 15 ± 0.2 mm. Coarse feed 300 or 900 µm/s. Section thickness 0–100 µm: 0–3 µm in 0.5 µm steps; 3–10 µm in 1 µm steps; 10–20 µm in 2 µm steps; 20–100 µm in 5 µm steps. Trimming 10–600 µm. Retraction 0–80 µm in 5 µm steps. Power supply 220 V ±10%, 50 Hz; power rating 1000 W.

Sample and consumable requirements

Material: fresh or properly fixed tissue fragments up to 35 × 35 mm, prepared according to the study protocol and oriented in a cryo-embedding medium (for example OCT or equivalent). Samples may be pre-frozen or frozen in the cryostat. Where required, the researcher supplies the cryo-embedding medium, disposable blades, slides (adhesive/charged for IF/IHC) and labeling. Potentially infectious samples may be processed only under an agreed biosafety protocol.

Data export format

Digital export is not provided. The output consists of physical frozen sections on slides for subsequent staining, immunolabeling, microscopy and/or digital scanning.

Operating instructions (SOP)

Before work, cool the cryochamber to the temperature recommended for the tissue type, securely mount the specimen and the blade and set the section thickness. After work, remove waste, carry out cleaning and disinfection and defrost the chamber according to schedule.

Responsible specialist

Valentyna Plotnykova
[email protected] | +380977303159

Available studies and methods

Brightfield light microscopy of histological and cytological preparations; assessment of slides stained with H&E and special histochemical methods; analysis of immunohistochemical preparations; morphological assessment, morphometry and photodocumentation.

Technical specifications

CFI60 Infinity optical system. High-brightness white LED illumination with Light Intensity Management, ECO and Sleep modes. Motorized six-position objective nosepiece. Coaxial coarse/fine focusing: 30 mm travel; coarse 9.33 mm per revolution; fine 0.1 mm per revolution; fine movement scale 1 µm. Stage travel 78 × 54 mm. Supported CFI eyepieces: 10× (22 mm field), 12.5×, 15×, UW 10× (25 mm field). Power consumption in the brightfield configuration approximately 13 W; weight of the standard binocular configuration approximately 15.4 kg.

Sample and consumable requirements

Prepared histological or cytological slides on clean glass slides with a coverslip; the slide must be labeled and free from excess mounting medium on the surface. Oil immersion objectives require the appropriate immersion oil. After working with immersion, lint-free lens tissue and the recommended cleaning agent are required.

Data export format

The microscope itself does not create a separate digital file. The output is a visual microscopic image, for example in TIFF or JPEG format, for subsequent morphometric analysis.

Operating instructions (SOP)

Before work, check that the optics are clean, switch on the LED illumination and set up Köhler illumination. Begin observation with a low-magnification objective and focus without allowing the objective to touch the glass. Use immersion oil only with the appropriate objective and clean the optics immediately after use.

Responsible specialist

Solomiia Kramar
[email protected] | +380961021042

Available studies and methods

Antigen retrieval; acceleration of selected special histochemical staining procedures.

Technical specifications

Benchtop multifunctional microwave processor. Maximum capacity up to 40 slides. 8-inch touch terminal with pre-saved protocols; built-in camera for process monitoring; infrared laser temperature sensor; reagent stirring system; connection to an extraction system and a built-in carbon filter. Standardized temperature and time protocols are provided for samples of different thickness and for various laboratory applications.

Sample and consumable requirements

Samples must be properly fixed, labeled and placed in dedicated plastic racks (section thickness 4–5 µm). The reagents required depend on the procedure: for antigen retrieval, a low- or high-pH buffer. A compatible KOS module is used.

Data export format

Digital export of analytical data is not the principal output. The output is physically prepared material.

Operating instructions (SOP)

Operation is permitted for trained personnel only. Before starting, select a validated protocol and the appropriate Histomodule, check sample labeling, reagent levels and compatibility, correct installation of the baskets and operation of the extraction system. Follow the prompts on the touch terminal during the run; after completion, clean the chamber and the reusable accessories according to the instructions.

Responsible specialist

Solomiia Kramar
[email protected] | +380961021042